Substituted oxime ethers, their preparation and their use for controlling pests and fungi

ABSTRACT

Substituted oxime ethers of the general formula I , haloalkyl, haloalkenyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, cyanoalkyl, alkoxycarbonylalkyl, arylalkyl, heteroarylalkyl, arylalkenyl or aryloxyalkyl, the aromatic or heteroaromatic ring being substituted or unsubstituted, R2 and R3 are hydrogen, alkyl, haloalkyl, alkoxy, haloalkoxy, halogen, cyano or nitro, R4 is hydrogen, alkyl, cycloalkyl, haloalkyl or aryl, the aromatic ring being substituted or unsubstituted, and R5 and R6 are identical or different and each is hydrogen or alkyl, and X is CH or N, and fungicides and pesticides containing these compounds.

This is a continuation of application Ser. No. 08/261,975 filed on Jun. 17, 1994, now abandoned, which is a division of application Ser. No. 08/091,254, filed on Jul. 15, 1993, now U.S. Pat. No. 5,358,968.

The present invention relates to novel substituted oxime ethers of the general formula I ##STR2## where R¹ is C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₄ -alkynyl, C₁ -C₆ -haloalkyl, C₃ -C₆ -haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl, C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl, cyano-C₁ -C₆ -alkyl, C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl, aryl-C₁ -C₆ -alkyl, hetaryl-C₁ -C₆ -alkyl, aryl-C₃ -C₆ -alkenyl or aryloxy-C₁ -C₆ -C-alkyl, where the aromatic or heteroaromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₃ -C₆ -cycloalkyl, C₁ -C₄ -alkoxy, C₁ or C₂ -haloalkoxy, halogen, aryl or aryloxy,

R² and R³ are identical or different and are each hydrogen, C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro,

R⁴ is hydrogen, C₁ -C₆ -alkyl C₃ -C₆ -cycloalkyl, C₁ -C₂ -haloalkyl or aryl, where the aromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro,

R⁵ and R⁶ are identical or different and are each hydrogen or C₁ -C₄ -alkyl and

X is CH or N.

The invention also relates to methods and intermediates for producing compounds I, fungicides containing them, and their use, pesticides containing them, and the use of compounds of the general formula IA ##STR3## where R¹, R², R³, R⁴ and X have the meanings given in claim 1 and Z is NR⁵ R⁶ or OR⁷, where R⁵ and R⁶ have the above meanings and R⁷ is C₁ -C₄ -alkyl, for controlling pests.

It is known that oxime ethers, for example methyl 2-(2'-methylphenoxymethyl)-phenylglyoxylate O-methyl oxime or methyl 2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenylglyoxylate O-methyl oxime, can be used as fungicides (European Patents 253,213, 386,561 and 398,692).

Further, EP-A 386 561 discloses compounds of the formula IA, Z being methoxy, as fungicidal active ingredients.

It is an object of the invention to provide novel compounds having improved and wider applicability in crop protection.

We have found that this object is achieved by compounds I defined at the outset, methods and intermediates for producing them, agents containing them and the use thereof for controlling fungi, and agents for controlling fungi and the use of compounds of the formula IA defined at the outset for controlling fungi.

In the general formulae I and IA, R¹ may be, for example, C₁ -C₆ -alkyl (C₁ -C₄ -alkyl) (eg. methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, isopentyl, sec-pentyl, tert-pentyl, neopentyl or hexyl), C₃ -C₆ -alkenyl (eg. allyl, 2-butenyl, 3-butenyl, 1-methyl-2-propenyl or 2-methyl-2-propenyl), C₃ - or C₄ -alkynyl (eg. propargyl or 2-butynyl), C₁ -C₆ -haloalkyl (eg. 2-fluoroethyl), C₃ -C₆ -haloalkenyl (eg. 3-chloroallyl), C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl (eg. 2-methoxyethyl or 3-ethoxypropyl), C₃ -C₆ -cycloalkyl (eg. cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl), C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl (eg. cyclopropylmethyl or cyclohexylmethyl), cyano-C₁ -C₆ -alkyl (eg. cyanomethyl or 3-cyanopropyl), C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl (eg. ethoxycarbonylmethyl, tert-butoxycarbonylmethyl or tert-butoxycarbonylpropyl), aryl-(phenyl)-C₁ -C₆ -alkyl (eg. benzyl, 2-phenylethyl, 3-phenylpropyl or 4-phenylbutyl), hetaryl-(pyridyl, thienyl)-C₁ -C₆ -alkyl (eg. pyrid-3-ylmethyl or thien-2-ylmethyl), aryl-(phenyl)-C₃ -C₆ -alkenyl (eg. 4-phenyl-2-butenyl or 4-phenyl-3-butenyl), or aryloxy-(phenoxy)-C₁ -C₆ -alkyl (eg. phenoxymethyl, phenoxyethyl, phenoxypropyl, phenoxybutyl, naphthyloxymethyl or naphthyloxyethyl), where the aromatic (phenyl) or heteroaromatic (pyridyl, thienyl) ring is unsubstituted or substituted by one or more, for example 1 to 5, in particular 1 to 3, of the following radicals:

C₁ -C₄ -alkyl (eg. methyl, ethyl, propyl or butyl), C₁ - or C₂ -haloalkyl (eg. trifluoromethyl or trichloromethyl), C₃ -C₆ -cycloalkyl (eg. cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl), C₁ -C₄ -alkoxy (eg. methoxy, ethoxy, propoxy or butoxy), C₂ - or C₂ -haloalkoxy (eg. trifluoromethoxy), halogen (eg. fluorine, chlorine or bromine), aryl (eg. phenyl) or aryloxy (eg. phenoxy),

R² and R³ may be identical or different and are each hydrogen, C₁ -C₄ -alkyl (eg. methyl, ethyl, n-propyl, isopropyl or butyl), C₁ - or C₂ -haloalkyl (eg. trifluoromethyl or trichloromethyl), C₁ -C₄ -alkoxy (eg. methoxy, ethoxy, n-propoxy, isopropoxy or butoxy), C₁ - or C₂ -haloalkoxy (eg. trifluoromethoxy), halogen (eg. fluorine, chlorine, bromine or iodine), cyano or nitro,

R⁴ may be, for example, C₁ -C₆ -alkyl, (C₁ -C₄ -alkyl) (eg. methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, isopentyl, sec-pentyl, tert-pentyl, neopentyl or hexyl) or aryl (eg. phenyl), where the aromatic ring is unsubstituted or substituted by one or more, for example 1 to 5, in particular 1 to 3, of the following radicals: C₁ -C₄ -alkyl (eg. methyl, ethyl, propyl or butyl), C₁ - or C₂ -haloalkyl (eg. trifluoromethyl or trichloromethyl), C₁ -C₄ -alkoxy (eg. methoxy, ethoxy, propoxy or butoxy), C₁ - or C₂ -haloalkoxy (eg. difluoromethoxy or trifluoromethoxy), halogen (eg. fluorine, chlorine, bromine or iodine), cyano or nitro, R⁵ and R⁶ may be identical or different and are each hydrogen or C₁ -C₄ -alkyl (eg. methyl, ethyl, n-propyl, isopropyl or butyl), preferred compounds being those in which R⁵ is hydrogen and R⁶ is methyl,

X may be CH or N, and R⁷ may be C₁ -C₄ -alkyl as mentioned above, especially methyl.

--C(R⁴)═N--O--R¹ may be in the 2-, 3- or, preferably, 4-position on the phenyl radical relative to --O--CH₂ --

Owing to the C═C or C═N double bonds, the novel compounds of the general formula I and IA may be obtained in the preparation as E/Z isomer mixtures. These may be separated into the individual components in a conventional manner, for example by crystallization or chromatography. Both the individual isomeric compounds and mixtures thereof are embraced by the invention and can be used as fungicides and pesticides. Regarding the group --C(CONR⁵ R⁶)═X--OCH₃, preferred compounds are those in which CONR⁵ R⁶ and OCH₃ at the C═X double bond have the E configuration. Regarding the group --C(R⁴)═N--OR¹, preferred compounds are those in which R⁴ and OR¹ on the C═N double bond have the cis configuration and in which the C═N double bond therefore has the E configuration in the case of small substituents, eg. methyl.

The novel compounds of the formula I are prepared, for example, by reacting a substituted oxime ether of the general formula II, where L is C₁ -C₄ -alkoxy, hydroxyl or halogen, such as chlorine or bromine, with a primary or secondary amine of the formula HNR⁵ R⁶. ##STR4##

Compounds of the formula II where L is C₁ -C₄ -alkoxy are disclosed in European Patent 386,561 or can be prepared by processes similar to those described there. The corresponding carboxylic acids II (L═OH) can be readily prepared therefrom by conventional processes (cf. for example Houben-Weyl, Vol. E 5, pages 223-254; Org. Reactions 24 (1976), 187-224). These can then be converted into activated carboxylic acid derivatives, examples being imidazolides II in which L is imidazol-1-yl or the acyl halides II in which L is Cl or Br (cf. for example Houben-Weyl, Vol. VIII, page 463 et seq.). Reaction of the compounds of the formula II with primary or secondary amines HNR⁵ R⁶ gives the corresponding amides of the general formula I (cf. for example Houben-Weyl, Vol. E 5, pages 941-977 and 983-991; Houben Weyl, Vol. VIII, page 654 et seq.).

R¹, R², R³, R⁴, R⁵, R⁶ and X have the above-mentioned meanings.

Compounds of the formula IA where Z is OR⁷ are known from EP-A 386,561 or may be produced by the methods described therein.

The Examples and methods which follow illustrate the preparation of the novel active ingredients and their intermediates.

PREPARATION EXAMPLE 1 N-Methyl-2-[2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl]-phenylglyoxylamide O-methyl oxime

a) 225.3 g (1.5 mol) of 4-hydroxy-2-methylacetophenone are dissolved in 600 ml of dry methanol. 150.3 g (1.8 mol) of methoxyamine hydrochloride and 100 g of a molecular sieve are added. Stirring is carried out for 12 hours at room temperature (20° C.). The molecular sieve is filtered off. The filtrate is evaporated down. The remaining residue is taken up in dichloromethane. The organic phase is washed with water, dried and evaporated down. The solid product obtained is washed with pentane and then dried. 252 g (94%) of 4-hydroxy-2-methylacetophenone O-methyl oxime are obtained in the form of a colorless crystalline solid (mp.: 96°-98° C.).

b) 89.6 g (0.5 mol) of 4-hydroxy-2-methylacetophenone O-methyl oxime in 300 ml of dry methanol are initially taken under nitrogen. 90 g (0.5 mol) of a 30% strength by weight sodium methylate solution are added dropwise. After 2 hours, the methanol is distilled off. The residue is dissolved in 700 ml of dimethylformamide. 15 g of potassium iodide are added. A solution of 151.6 g (0.53 mol) of methyl 2-(bromomethyl)-phenylglyoxylate O-methyl oxime in 300 ml of methanol are then added dropwise at room temperature under nitrogen. Stirring is carried out for about 10 hours at room temperature, after which the mixture is cooled to about 10° C. and water is added dropwise. The precipitate formed is filtered off, washed with water and pentane and dried. 153.7 g (80%) of methyl 2-[2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl]-phenylglyoxylate O-methyl oxime are obtained as a colorless crystalline solid (mp.: 138°-140° C.).

c) 4.8 g (0.012 mol) of methyl 2-[2'-methyl-4'-(methoximinoeth-1'-yl)-phenoxymethyl]-phenylglyoxylate O-methyl oxime are dissolved in 32 ml of tetrahydrofuran, and 3.6 g (0.047 mol) of a 40% strength aqueous methylamine solution are added. Thereafter, the reaction mixture is stirred for 6 hours at 40° C. and then evaporated down. The residue was taken up in methyl tert-butyl ether. The organic phase is washed with water, dried and evaporated down again. The remaining crude product is purified by chromatography over a silica gel column (1:1 cyclohexane/ethyl acetate). 3.2 g (67%) of N-methyl-2-[2'-methyl-4'-(methoxyminoeth-1"-yl)-phenoxymethyl]phenylglyoxylamide O-methyl oxime are obtained in the form of colorless crystals (mp.: 104°-105° C., compound No. I.007).

PREPARATION EXAMPLE 2 N-Methyl-α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)phenoxymethyl)-phenyl]-β-methoxyacrylamide

a) Methyl α-(2-bromomethylphenyl)-β-methoxyacrylate and 4-hydroxy-2-methylacetophenone O-methyl oxime are reacted similarly to Method b) (Example 1) to give methyl α-[2-(2'-methyl-4'-(methoximinoeth-1'-yl)phenoxymethyl)-phenyl]-8-methoxyacrylate. The compound is obtained as a colorless solid (mp.: 118°-120° C.).

b) 3 g (0. 0078 mol) of methyl α-[2-(2'-methyl-4-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-.beta.-methoxyacrylate are dissolved in 15 ml of dry pyridine. 5.2 g (0.039 mol) of anhydrous lithium iodide are added and stirring is carried out for 8 hours at 130° C. The reaction mixture is evaporated down. The residue is taken up in water. The aqueous phase is first washed with methyl tert-butyl ether and then acidified with hydrochloric acid. The aqueous phase is then extracted with methyl tert-butyl ether. The methyl tert-butyl ether phase is washed with water, dried over sodium sulfate and evaporated down. 2.1 g of α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-.beta.-methoxyacrylic acid are obtained as a dark resin, which is used for the subsequent reactions without further purification.

c) 2.1 g (0.0056 mol) of α-[2-(2'-methyl-4'-(methoximinoeth- 1"-yl)-phenoxymethyl)-phenyl]-β-methoxyacrylic acid and 0.53 g of pyridine in 10 ml of dried diethyl ether are initially taken. 0.8 g (0.0067 mol) of thionyl chloride is added dropwise at 0°-5° C. and stirring is carried out for 10 hours at room temperature. The mixture is filtered. The filtrate is evaporated down. 2 g of α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)phenoxymethyl)-phenyl]-.beta.-methoxyacryloyl chloride are obtained as a dark oil, which is used for the subsequent reactions without further purification.

d) 1 g (0.0026 mol) of α-[2-(2'-methyl-4'-(methoximinoeth-1'-yl)-phenoxymethyl)-phenyl]-.beta.-methoxyacryloyl chloride in 10 ml of dichloromethane is initially taken. A solution of 1 g (0.032 mol) of methylamine in 10 ml of dichloromethane is added dropwise at 0°-5° C. Stirring is carried out for 10 hours at room temperature. The reaction mixture is taken up in 20 ml of dichloromethane and the solution is washed with water, dried and evaporated down. The remaining crude product is purified by chromatography over a silica gel column (2:1 n-hexane/acetone). 0.5 g (50%) of N-methyl-α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-β-methoxyacrylamide is obtained in the form of colorless crystals (mp.: 96°-98° C., compound No. I.006).

Compounds I (and IA in which Z is NR⁵ R⁶) listed in the Table below may be prepared similarly. Compounds IA where Z is OR⁷ may be obtained in accordance with the details given in EP-A 386,561. They too are listed in the Table below.

Compounds I (and IA in which Z is NR⁵ R⁶) of particular significance with regard to their biological action on pests (plant-pathogenic fungi, and insects, mites and nematodes) are listed in Tables 1, 2, 5-11 and 18-22 which follow.

Further, compounds IA in which Z is OR⁷ which are of particular significance with regard to their biological action on animal pests (insects, mites and nematodes) are listed in Tables 3, 4, 12-17 and 23-27.

    __________________________________________________________________________      ##STR5##     No.        R.sup.1           R.sup.2                                R.sup.3                                    P*                                      R.sup.4                                            Z      X  Phys. data     __________________________________________________________________________     I.001        CH.sub.3          H     H   3 CH.sub.3                                            NHCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      2.19(s, 3H);                                                      2.86(d, 3H); 3.93(s,                                                      3H);                                                      3.99(s, 3H); 4.95(s,                                                      2H);                                                      6.7(sbr, 1H),                                                      6.84-7.52(m, 8H)     I.002        C.sub.2 H.sub.5   H     H   3 CH.sub.3                                            NHCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      1.13(t, 3H);                                                      2.29(s, 3H); 2.85(d,                                                      3H);                                                      3.39(s, 3H): 4.23(q,                                                      2H);                                                      4.96(s, 2H); 6.75(sbr,                                                      1H);                                                      6.86-7.55(m, 8H)     I.003        CH.sub.2 CHCH.sub.2                          H     H   3 CH.sub.3                                            NHCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      2.2(d, 3H);                                                      2.86(d, 3H); 3.92(s,                                                      3H);                                                      4.69(m, 2H); 4.96(s,                                                      2H);                                                      5.17-5.38(m, 2H);                                                      5.96-6.17(m, 1H);                                                      6.37(sbr, 1H);                                                      6.84-7.54(m, 8H)     I.004        CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 101-103° C.                                                      (E; E)     I.005        CH.sub.3          2-Cl  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 123-124° C.                                                      (E; E)     I.006        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   CH mp: 96-98° C. (E;                                                      E)     I.007        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 104-105° C.                                                      (E; E)     I.008        CH.sub.3          2-OCH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 78-80° C. (E;                                                      E)     I.009        CH.sub.3          3-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 89-90° C. (E;                                                      E)     I.010        C.sub.2 H.sub.5   2-Cl  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 107-108° C.                                                      (E; E)     I.011        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 92-94° C. (E;                                                      E)     I.012        C.sub.2 H.sub.5   2-OCH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 78-81° C. (E;                                                      E)     I.013        C.sub.2 H.sub.5   3-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  resin (E; E)     I.014        CH.sub.3          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      2.13(s, 3H);                                                      2.18(s, 3H); 2.28(s,                                                      3H);                                                      2.87(d, 3H); 3.95("s",                                                      6H);                                                      4.92(s, 2H); 6.61(s,                                                      1H);                                                      6.72(sbr, 1H); 7.00(s,                                                      1H);                                                      17.19-7.56(m, 4H)     I.015        CH.sub.3          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR (ppm):                                                      1.1(t, 3H);                                                      2.23(s, 3H); 2.7(q,                                                      2H);                                                      2.86(d, 3H); 3.93(s,                                                      3H);                                                      3.96(s, 3H) 4.98(s,                                                      2H);                                                      6.92(sbr, 1H);                                                      6.75-7.55(m, 7H)     I.016        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 98-106° C.                                                      (E; E)     I.017        C.sub.2 H.sub.5   2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  resin (E; E)                                                      .sup.1 H-NMR(ppm):                                                      1.3(t, 3H);                                                      2.15(s, 3H); 2.17(s,                                                      3H);                                                      2.29(s, 3H); 2.87(d,                                                      3H);                                                      3.95(s, 3H); 4.18(q,                                                      2H);                                                      4.94(s, 2H); 6.61(s,                                                      1H);                                                      6.72(sbr, 1H); 6.99(s,                                                      1H);                                                      7.2-7.57(m, 4H)     I.018        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 72-73° C. (E;                                                      E)     I.019        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 54-56° C. (E;                                                      E)     I.020        (CH.sub.2).sub.5 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 96-98° C. (E;                                                      E)     I.021        CH.sub.2 CHCH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 61-63° C. (E;                                                      E)     I.022        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 49-52° C. (E;                                                      E)     I.023        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 71-73° C. (E;                                                      E)     I.024        CH.sub.3          2-CH.sub.3                                H   4 CH(CH.sub.3).sub.2                                            NHCH.sub.3                                                   N  resin (E; E)     I.025        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 94-96° C. (E;                                                      E)     I.026        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 76-79° C. (E;                                                      E)     I.027        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 86-88° C. (E;                                                      E)     I.028        (CH.sub.2).sub.2 OCH).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  resin (E; E)     I.029        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.030        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 74-76° C. (E;                                                      E)     I.031        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 87-89° C. (E;                                                      E)     I.032        CH.sub.3          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.033        C.sub.2 H.sub.5   2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.034        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 58-66° C. (E;                                                      E)     I.035        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.036        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.037        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 58-60° C. (E;                                                      E)     I.038        (CH.sub.2).sub.2 CH.sub.3                          2-Cl  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 84-86° C. (E;                                                      E)     I.039        (CH.sub.2).sub.3 CH.sub.3                          2-Cl  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 92-94° C. (E;                                                      E)     I.040        CH.sub.2 CHCH.sub.2                          2-Cl  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 80-82° C. (E;                                                      E)     I.041        CH.sub.3          2-CH.sub.3                                H   4 (CH.sub.2).sub.2 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 105-107° C.                                                      (E; E)     I.042        (CH.sub.2).sub.5 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 52-54° C. (E;                                                      E)     I.043        CH.sub.2 C CH     2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 142-144° C.                                                      (E; E)     I.044        CH.sub.2 C CH     2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 88-90° C. (E;                                                      E)     I.045        CH.sub.2 C CH     2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 99-101° C.                                                      (E; E)     I.046        CH.sub.2 CH CHCl  2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 67-69° C. (E;                                                      E)     I.047        CH.sub.2 CH CHCl  2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            NHCH.sub.3                                                   N  mp: 108-110° C.                                                      (E; E)     I.048        CH.sub.2 CH CHCl  2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 110-112° C.                                                      (E; E)     I.049        CH.sub.2 CN       2-CH.sub.3                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 114-116° C.                                                      (E; E)     I.050        CH.sub.2 CN       2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 104-106° C.                                                      (E; E)     I.051        CH.sub.3          2-CH.sub.3                                H   4 C.sub.6 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.052        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 C.sub.6 H.sub.5                                            NHCH.sub.3                                                   N  resin (E; E)     I.053        CH.sub.3          H     H   2 H     OCH.sub.3                                                   CH mp: 82-84° C. (E;                                                      E)     I.054        CH.sub.3          H     H   2 H     OCH.sub.3                                                   N  mp: 73-76° C. (E;                                                      E)     I.055        C.sub.2 H.sub.5   H     H   2 H     OCH.sub.3                                                   CH mp: 86-88° C. (E;                                                      E)     I.056        C.sub.2 H.sub.5   H     H   2 H     OCH.sub.3                                                   N  mp: 89-90° C. (E;                                                      E)     I.057        C.sub.2 H.sub.5   4-Cl  H   2 H     OCH.sub.3                                                   CH mp: 95-97° C. (E;                                                      E)     I.058        CH.sub.3          H     H   3 H     OCH.sub.3                                                   CH mp: 75-77° C. (E;                                                      E)     I.059        CH.sub.3          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.060        C.sub.2 H.sub.5   H     H   3 H     OCH.sub.3                                                   CH oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      1.28(t, 3H);                                                      3.69(s, 3H); 3.73(s,                                                      3H);                                                      4.20(q, 2H); 4.97(s,                                                      2H);                                                      6.85-7.53(m, 8H);                                                      7.57(s, 1H); 8.0(s, 1H)     I.061        C.sub.2 H.sub.5   H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.062        C.sub.2 H.sub.5   6-OCH.sub.3                                H   3 H     OCH.sub.3                                                   CH mp: 96-98° C. (E;                                                      E)     I.063        C.sub.2 H.sub.5   6-OCH.sub.3                                H   3 H     OCH.sub.3                                                   N  mp: 124-126° C.                                                      (E; E)     I.064        CH.sub.2 CHCH.sub.2                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.065        CH.sub.2 CHCH.sub.2                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.066        CH(CH.sub.3).sub.2                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.067        CH(CH.sub.3).sub.2                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.068        (CH.sub.2).sub.3 CH.sub.3                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.069        (CH.sub.2).sub.3 CH.sub.3                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.070        (CH.sub.2).sub.5 CH.sub.3                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.071        (CH.sub.2).sub.5 CH.sub.3                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.072        CH.sub.2 C.sub.6 H.sub.5                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.073        CH.sub.2 C.sub.6 H.sub.5                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.074        C.sub.2 H.sub.5   6-OC.sub.2 H.sub.5                                H   3 H     OCH.sub.3                                                   CH mp: 83-85° C. (E;                                                      E)     I.075        C.sub.2 H.sub.5   6-OC.sub.2 H.sub.5                                H   3 H     OCH.sub.3                                                   N  mp: 104-106° C.                                                      (E; E)     I.076        (CH.sub.2).sub.4 CH.sub.3                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.077        CH.sub.2 -(2F-ab,4 C.sub.6 H.sub.4)                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.078        CH.sub.2 -(2F-ab,4 C.sub.6 H.sub.4)                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.079        CH.sub.2 -(3F-ab,4 C.sub.6 H.sub.4)                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.080        CH.sub.2 -(3F-ab,4 C.sub.6 H.sub.4)                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.081        CH.sub.2 -(2-ClC.sub.6 H.sub.4)                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.082        (3,4-Cl.sub.2C.sub.6 H.sub.3)CH.sub.2                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.083        (3,4-Cl.sub.2C.sub.6 H.sub.3)CH.sub.2                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.084        (2,6-Cl.sub.2C.sub.6 H.sub.3)CH.sub.2                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.085        (2,6-Cl.sub.2C.sub.6 H.sub.3)CH.sub.2                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.086        (CH.sub.2).sub.2 C.sub.6 H.sub.5                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.087        (CH.sub.2).sub.2 C.sub.6 H.sub.5                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.088        (CH.sub.2).sub.2 CHCHC.sub.6 H.sub.5                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.089        (CH.sub.2).sub.2 CHCHC.sub.6 H.sub.5                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.090        (4-ClC.sub.6 H.sub.4)CH.sub.2 CHCHCH.sub.2                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.091        (4-ClC.sub.6 H.sub.4)CH.sub.2 CHCHCH.sub.2                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.092        (4-CF.sub.3C.sub.6 H.sub.4)CH.sub.2 CHCHCH.sub.2                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.093        (4-CF.sub.3C.sub.6 H.sub.4)CH.sub.2 CHCHCH.sub.2                          H     H   3 H     OCH.sub.3                                                   N  oil (E; E)     I.094        CH.sub.3          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.095        CH.sub.3          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)     I.096        C.sub.2 H.sub.5   H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      1.32(t, 3H);                                                      2.18(s, 3H); 3.68(s,                                                      3H);                                                      3.77(s, 3H); 4.22(q,                                                      2H);                                                      4.97(s, 2H); 6.83-7.53                                                      (m, 8H); 7.55(s, 1H)     I.097        C.sub.2 H.sub.5   H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      1.32(t, 3H);                                                      2.17(s, 3H); 3.82(s,                                                      3H);                                                      4.0(s, 3H); 4.23(q,                                                      4H);                                                      4.97(s, 2H);                                                      6.82-7.57(m, 8H)     I.098        (CH.sub.2).sub.2 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.099        (CH.sub.2).sub.2 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  mp: 73-74° C. (E;                                                      E)     I.100        CH.sub.2 CHCH.sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.101        CH.sub.2 CHCH.sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  mp: 51-53° C. (E;                                                      E)     I.102        CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.103        CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  mp: 58-60° C. (E;                                                      E)     I.104        (CH.sub.2).sub.3 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.105        (CH.sub.2).sub.3 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      0.95(t, 3H);                                                      1.43(m, 2H); 1.7(m,                                                      2H);                                                      2.18(s, 3H); 3.83(s,                                                      3H);                                                      4.0(s, 3H); 4.17(t,                                                      2H);                                                      4.97(s, 2H);                                                      6.82-7.55(m, 8H)     I.106        CH.sub.2 CHCHCH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.107        CH.sub.2 CHCHCH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  mp: 76-78° C. (E;                                                      E)     I.108        (CH.sub.2).sub.5 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.109        (CH.sub.2).sub.5 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      0.87(t, 3H);                                                      1.32(m, 6H); 1.7(m,                                                      2H);                                                      2.18(s, 3H); 3.83(s,                                                      3H);                                                      4.02(s, 3H); 4.17(t,                                                      2H);                                                      4.95(s, 2H);                                                      6.83-7.57(m, 8H)     I.110        CH.sub.2 C.sub.6 H.sub.5                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)                                                      .sup.1H NMR(ppm):                                                      2.22(s, 3H);                                                      3.78(s, 3H); 4.0(s,                                                      3H);                                                      4.97(s, 2H); 5.23(s,                                                      2H);                                                      6.82-7.53(m, 8H)     I.111        CH.sub.2 CHCHCl   H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.112        CH.sub.2 CHCHCl   H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)     I.113        C(CH.sub.3).sub.2 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.114        C(CH.sub.3).sub.2 CH.sub.3                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  mp: 83-85° C. (E;                                                      E)     I.115        CH.sub.2 CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.116        CH.sub.2 CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  mp: 70-72° C. (E;                                                      E)     I.117        CH.sub.2 C(CH.sub.3)CH.sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.118        CH.sub.2 C(CH.sub.3)CH.sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 64-65° C. (E;                                                      E)     I.119        (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.120        (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)     I.121        CH.sub.3          H     H   4 H     OCH.sub.3                                                   CH mp: 84-86° C. (E;                                                      E)     I.122        CH.sub.3          H     H   4 H     OCH.sub.3                                                   N  mp: 88-91° C. (E;                                                      E)     I.123        CH.sub.3          2-OCH.sub.3                                H   4 H     OCH.sub.3                                                   CH oil (E; E)     I.124        CH.sub.3          2-OCH.sub.3                                H   4 H     OCH.sub.3                                                   N  mp: 105-107° C.                                                      (E; E)     I.125        C.sub.2 H.sub.5   H     H   4 H     OCH.sub.3                                                   CH mp: 108-110° C.                                                      (E; E)     I.126        C.sub.2 H.sub.5   H     H   4 H     OCH.sub.3                                                   N  mp: 106-108° C.                                                      (E; E)     I.127        CH.sub.2 CHCH.sub.2                          H     H   4 H     OCH.sub.3                                                   CH mp: 103-105° C.                                                      (E; E)     I.128        CH.sub.2 CHCH.sub.2                          H     H   4 H     OCH.sub.3                                                   N  mp: 82-84° C. (E;                                                      E)     I.129        (CH.sub.2).sub.5 CH.sub.3                          H     H   4 H     OCH.sub.3                                                   CH mp: 62-63° C. (E;                                                      E)     I.130        (CH.sub.2).sub.5 CH.sub.3                          H     H   4 H     OCH.sub.3                                                   N  mp: 72-73° C. (E;                                                      E)     I.131        CH.sub.2 C.sub.6 H.sub.5                          H     H   4 H     OCH.sub.3                                                   N  mp: 103-105° C.                                                      (E; E)     I.132        CH.sub.2 -(4-ClC.sub.6 H.sub.4)                          H     H   4 H     OCH.sub.3                                                   CH mp: 151-153° C.                                                      (E; E)     I.133        CH.sub.2 CHCHCl   H     H   4 H     OCH.sub.3                                                   CH oil (E; E)     I.134        CH.sub.2 CHCHCl   H     H   4 H     OCH.sub.3                                                   N  mp: 95-97° C. (E;                                                      E)     I.135        CH.sub.2 C(CH.sub.3)CH.sub.2                          H     H   4 H     OCH.sub.3                                                   CH mp: 100-102° C.                                                      (E; E)     I.136        CH.sub.2 C(CH.sub.3)CH.sub.2                          H     H   4 H     OCH.sub.3                                                   N  mp: 95-96° C. (E;                                                      E)     I.137        (CH.sub.2).sub.4 CH.sub.3                          H     H   4 H     OCH.sub.3                                                   N  oil (E; E)     I.138        CH.sub.3          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.139        CH.sub.3          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 99-100° C.                                                      (E; E)     I.140        CH.sub.3          2-Cl  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 93-94° C. (E;                                                      E)     I.141        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 137-139° C.                                                      (E; E)     I.142        CH.sub.3          2-OCH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 82-84° C. (E;                                                      E)     I.143        CH.sub.3          3-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 55-56° C. (E;                                                      E)     I.144        C.sub.2 H.sub.5   H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 71-73° C. (E;                                                      E)     I.145        C.sub.2 H.sub.5   H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 79-80° C. (E;                                                      E)     I.146        C.sub.2 H.sub.5   2-Cl  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 88-90° C. (E;                                                      E)     I.147        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 109-111° C.                                                      (E; E)     I.148        C.sub.2 H.sub.5   2-OCH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 96-98° C. (E;                                                      E)     I.149        C.sub.2 H.sub.5   3-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  resin (E; E)     I.150        (CH.sub.2).sub.2 CH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 87-99° C. (E;                                                      E)     I.151        (CH.sub.2).sub.2 CH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 100-101° C.                                                      (E; E)     I.152        CH.sub.2 CHCH.sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 90-92° C. (E;                                                      E)     I.153        CH.sub.2 CHCH.sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 107-108° C.                                                      (E; E)     I.154        CH(CH.sub.3).sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 120-123° C.                                                      (E; E)     I.155        CH(CH.sub.3).sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 109-110° C.                                                      (E; E)     I.156        (CH.sub.2).sub.3 CH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 64-66° C. (E;                                                      E)     I.157        (CH.sub.2).sub.3 CH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)                                                      .sup.1 H-NMR(ppm):                                                      0.97(t, 3H);                                                      1.4(m, 2H); 1.68(m,                                                      2H);                                                      2.17(s, 3H); 3.83(s,                                                      3H);                                                      4.0(s, 3H); 4.15(t,                                                      2H);                                                      4.95(s, 2H);                                                      6.82-7.57(m, 8H)     I.158        CH.sub.2 CHCHCH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.159        CH.sub.2 CHCHCH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 100-103° C.                                                      (E; E)     I.160        (CH.sub.2).sub.5 CH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 65-67° C. (E;                                                      E)     I.161        (CH.sub.2).sub.5 CH.sub.3                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 60-63° C. (E;                                                      E)     I.162        CH.sub.2 C.sub.6 H.sub.5                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 110-112° C.                                                      (E; E)     I.163        CH.sub.2 C.sub.6 H.sub.5                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 104-106° C.                                                      (E; E)     I.164        CH.sub.2 CHCHCI   H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 98-100° C.                                                      (E; E)     I.165        CH.sub.2 CHCHCI   H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 105-107° C.                                                      (E; E)     I.166        C(CH.sub.3).sub.3 H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 88-90° C. (E;                                                      E)     I.167        C(CH.sub.3).sub.3 H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 75-78° C. (E;                                                      E)     I.168        CH.sub.2 CH(CH.sub.3).sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 85-87° C. (E;                                                      E)     I.169        CH.sub.2 CH(CH.sub.3).sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 79-81° C. (E;                                                      E)     I.170        CH.sub.2 C(CH.sub.3)CH.sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 94-96° C. (E;                                                      E)     I.171        CH.sub.2 C(CH.sub.3)CH.sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 88-89° C. (E;                                                      E)     I.172        (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 46-48° C. (E;                                                      E)     I.173        (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                          H     H   4 CH.sub.3                                            OCH.sub.3                                                   N  oil (E; E)     I.174        CH.sub.3          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 104-107° C.                                                      (E; E)     I.175        CH.sub.3          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 84-87° C. (E;                                                      E)     I-176        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 78-80° C. (E;                                                      E)     I.177        C.sub.2 H.sub.5   2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 79-81° C. (E;                                                      E)     I.178        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 88-89° C. (E;                                                      E)     I.179        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 77-79° C. (E;                                                      E)     I.180        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 65-68° C. (E;                                                      E)     I.181        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 58-62° C. (E;                                                      E)     I.182        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 69-71° C. (E;                                                      E)     I.183        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 73-75° C. (E;                                                      E)     I.184        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 44-45° C. (E;                                                      E)     I.185        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 90-92° C. (E;                                                      E)     I.186        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 85-87° C. (E;                                                      E)     I.187        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 65-68° C. (E;                                                      E)     I.188        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 92-93° C. (E;                                                      E)     I.189        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 82-84° C. (E;                                                      E)     I.190        CH.sub.3          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 109-111° C.                                                      (E; E)     I.191        C.sub.2 H.sub.5   2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 87-89° C. (E;                                                      E)     I.192        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 99-100° C.                                                      (E; E)     I.193        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 83-85° C. (E;                                                      E)     I.194        (CH.sub.2).sub.2 OCH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 81-83° C. (E;                                                      E)     I.195        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 81-83° C. (E;                                                      E)     I.196        (CH.sub.2).sub.2 CH.sub.3                          2-Cl  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 67-70° C. (E;                                                      E)     I.197        (CH.sub.2).sub.3 CH.sub.3                          2-Cl  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 66-68° C. (E;                                                      E)     I.198        CH.sub.2 CHCH.sub.2                          2-Cl  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 91-92° C. (E;                                                      E)     I.199        CH.sub.2 CHCH     2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 107-109° C.                                                      (E; E)     I.200        CH.sub.2 CHCH     2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 100-102° C.                                                      (E; E)     I.201        CH.sub.2 CHCH     2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 87-89° C. (E;                                                      E)     I.202        CH.sub.2 CHCHCl   2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 118-120° C.                                                      (E; E)     I.203        CH.sub.2 CHCHCl   2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 95-97° C. (E;                                                      E)     I.204        CH.sub.2 CHCHCl   2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 89-91° C. (E;                                                      E)     I.205        CH.sub.3          2-CH.sub.3                                H   4 C.sub.6 H.sub.5                                            OCH.sub.3                                                   N  resin (E; E)     I.206        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 C.sub.6 H.sub.5                                            OCH.sub.3                                                   N  resin (E; E)     I.207        CH.sub.2 CO.sub.2 C(CH.sub.3).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  resin (E; E)     I.208        (CH.sub.2).sub.3CO.sub.2 C(CH.sub.3).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 67-69° C. (E;                                                      E)     I.209        (CH.sub.2).sub.4CO.sub.2 C(CH.sub.3).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 54-56° C. (E;                                                      E)     I.210        (CH.sub.2).sub.4CO.sub.2 C(CH.sub.3).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH resin (E; E)     I.211        (CH.sub.2).sub.5CO.sub.2 C(CH.sub.3).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 46-48° C. (E;                                                      E)     I.212        (CH.sub.2).sub.5CO.sub.2 C(CH.sub.3).sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 56-58° C. (E;                                                      E)     I.213        CH.sub.2 CH CH    2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  resin (E; E)     I.214        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            N(CH.sub.3).sub.2                                                   N  mp: 78-80° C. (E;                                                      E)     I.215        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            N(CH.sub.3).sub.2                                                   CH resin (E; E)     I.216        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 CH.sub.3                                            N(CH.sub.3).sub.2                                                   N  resin (E; E)     I.217        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            NH.sub.2                                                   CH mp: 143-144° C.                                                      (E; E)     I.218        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            NHC.sub.2 H.sub.5                                                   CH mp: 110-111° C.                                                      (E; E)     I.219        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            N(CH.sub.3)C.sub.2 H.sub.5                                                   CH resin (E; E)     I.220        CH.sub.3          2-CH.sub.3                                H   4 c-C.sub.3 H.sub.5                                            NHCH.sub.3                                                   N  .sup.1 H-NMR (ppm):                                                      0.6-2.79(m, 5H); 2.2(s,                                                      3H);                                                      2.9(d, 3H); 3.9(s, 3H);                                                      3.95(s, 3H); 4.97(s,                                                      2H);                                                      6.7-7.6(m,6H)     I.221        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 c-C.sub.3 H.sub.5                                            NHCH.sub.3                                                   N  .sup.1 H-NMR (ppm):                                                      0.6-1.8(m, 8H); 2.2(s,                                                      3H);                                                      2.88(d, 3H); 3.95(s,                                                      3H);                                                      4.2(q, 2H); 4.93(s,                                                      2H);                                                      6.7-7.6(m, 8H)     I.222        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 c-C.sub.3 H.sub.5                                            NHCH.sub.3                                                   N  .sup.1 H-NMR(ppm):                                                      0.6-1.78(m, 10H);                                                      2.2(s, 3H); 2.9(d, 3H);                                                      3.92(s, 3H); 4.1(t,                                                      2H);                                                      4.97(s, 2H); 6.62-7.9(m,                                                      8H)     I.223        CH.sub.3          2-Cl  5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 80-83° C. (E;                                                      E)     I.224        C.sub.2 H.sub.5   2-Cl  5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 96-98° C. (E;                                                      E)     I.225        CH.sub.3          2-Cl  5-Cl                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 121-122° C.                                                      (E; E)     I.226        C.sub.2 H.sub.5   2-Cl  5-Cl                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 105-107° C.                                                      (E; E)     I.227        CH.sub.3          2-F   H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 80-81° C. (E;                                                      E)     I.228        C.sub.2 H.sub.5   2-F   H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 63-64° C. (E;                                                      E)     I.229        (CH.sub.2).sub.2 CH.sub.3                          2-F   H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 86-87° C. (E;                                                      E)     I.230        (CH.sub.2)3CH.sub.3                          2-F   H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 49-51° C. (E;                                                      E)     I.231        CH.sub.2 CHCH.sub.2                          2-F   H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 82-83° C. (E;                                                      E)     I.232        CH.sub.3          2-Br  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 136-138  C. (E; E)     I.233        C.sub.2 H.sub.5   2-Br  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 115-117° C.                                                      (E; E)     I.234        (CH.sub.2).sub.2 CH.sub.3                          2-Br  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 95-96° C. (E;                                                      E)     I.235        (CH.sub.2).sub.3 CH.sub.3                          2-Br  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 102-103° C.                                                      (E; E)     I.236        CH.sub.2 CHCH.sub.2                          2-Br  H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 119-120° C.                                                      (E; E)     I.237        CH.sub.3          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 89-91° C. (E;                                                      E)     I.238        C.sub.2 H.sub.5   2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 83-84° C. (E;                                                      E)     I.239        (CH.sub.2).sub.2 CH.sub.3                          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 87-88° C. (E;                                                      E)     I.240        (CH.sub.2).sub.3 CH.sub.3                          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 84-85° C. (E;                                                      E)     I.241        CH.sub.2 CHCH.sub.2                          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 82-83° C. (E;                                                      E)     I.242        (CH.sub.2).sub.2 CH.sub.3                          2-Cl  5-Cl                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 89-91° C. (E;                                                      E)     I.243        (CH.sub.2).sub.2 CH.sub.3                          2-Cl  5-CH.sub.3                                    4 CH.sub.3                                            NHCH.sub.3                                                   N  mp: 85-86° C. (E;                                                      E)     I.244        CH.sub.3          2-Cl  5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  resin (E; E)     I.245        C.sub.2 H.sub.5   2-Cl  5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 65-67° C. (E;                                                      E)     I.246        CH.sub.3          2-Cl  5-Cl                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 73-74° C. (E;                                                      E)     I.247        C.sub.2 H.sub.5   2-Cl  5-Cl                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 79-80° C. (E;                                                      E)     I.248        CH.sub.3          2-F   H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 88-89° C. (E;                                                      E)     I.249        C.sub.2 H.sub.5   2-F   H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 65-66° C. (E;                                                      E)     I.250        (CH.sub.2).sub.2 CH.sub.3                          2-F   H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 103-104° C.                                                      (E; E)     I.251        (CH.sub.2).sub.3 CH.sub.3                          2-F   H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 84-86° C. (E;                                                      E)     I.252        CH.sub.3 CHCH.sub.2                          2-F   H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 107-109° C.                                                      (E; E)     I.253        CH.sub.3          2-Br  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 90-91° C. (E;                                                      E)     I.253        CH.sub.3          2-Br  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 90-91° C. (E;                                                      E)     I.254        C.sub.2 H.sub.5   2-Br  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 103-104° C.                                                      (E; E)     I.255        (CH.sub.2).sub.2 CH.sub.3                          2-Br  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 86-87° C. (E;                                                      E)     I.256        (CH.sub.2).sub.3 CH.sub.3                          2-Br  H   4 CH.sub.3                                            OCH).sub.3                                                   N  mp: 68-69° C. (E;                                                      E)     I.257        CH.sub.2 CHCH.sub.2                          2-Br  H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 96-97° C. (E;                                                      E)     I.258        CH.sub.3          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 64-66° C. (E;                                                      E)     I.259        C.sub.2 H.sub.5   2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 56-57° C. (E;                                                      E)     I.260        (CH.sub.2).sub.2 CH.sub.3                          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 52-53° C. (E;                                                      E)     I.261        (CH.sub.2).sub.3 CH.sub.3                          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 40-41° C. (E;                                                      E)     I.262        CH.sub.2 CHCH.sub.2                          2-C.sub.2 H.sub.5                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  resin (E; E)     I.263        (CH.sub.2).sub.2 CH.sub.3                          2-Cl  5-Cl                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 80-81° C. (E;                                                      E)     I.264        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-Cl                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 56-58° C. (E;                                                      E)     I.265        CH.sub.2 CHCHCH.sub.3                          H     H   3 H     OCH.sub.3                                                   CH mp: 74-76° C. (E;                                                      E)     I.266        CH.sub.2 CHCHCl   H     H   3 H     OCH.sub.3                                                   CH mp: 56-58° C. (E;                                                      E)     I.267        CH.sub.2 CH(CH.sub.3).sub.2                          H     H   3 H     OCH.sub.3                                                   CH mp: 52-54° C. (E;                                                      E)     I.268        (CH.sub.2).sub.4 CH.sub.3                          H     H   3 H     OCH.sub.3                                                   CH oil (E; E)     I.269        CH.sub.2 C.sub.6 H.sub.5                          H     H   3 CH.sub.3                                            OCH.sub.3                                                   CH oil (E; E)     I.270        CH.sub.2 CHCHCH.sub.3                          H     H   4 H     OCH.sub.3                                                   CH mp: 86-88° C. (E;                                                      E)     I.271        CH.sub.2 CH(CH.sub.3).sub.2                          H     H   4 H     OCH.sub.3                                                   CH mp: 97-99° C. (E;                                                      E)     I.272        (CH.sub.2).sub.4 CH.sub.3                          H     H   4 H     OCH.sub.3                                                   CH mp: 84-86° C. (E;                                                      E)     I.273        CH.sub.3          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 118-120° C.                                                      (E; E)     I.274        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 101-103° C.                                                      (E; E)     I.275        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 113-115° C.                                                      (E; E)     I.276        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 113-115° C.                                                      (E; E)     I.277        CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 81-82° C. (E;                                                      E)     I.278        CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 80-81° C. (E;                                                      E)     I.279        CH.sub.2 CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 117-119° C.                                                      (E; E)     I.280        CH.sub.2 CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 91-93° C. (E;                                                      E)     I.281        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 97-99° C. (E;                                                      E)     I.282        C(CH.sub.3).sub.3 2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 83-85° C. (E;                                                      E)     I.283        C(CH.sub.3).sub.3 2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 86-88° C. (E;                                                      E)     I.284        CH.sub.2 C(CH.sub.3)CH.sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 106-108° C.                                                      (E; E)     I.285        CH.sub.2 C(CH.sub.3)CH.sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 51-54° C. (E;                                                      E)     I.286        (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 72-74° C. (E;                                                      E)     I.287        (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 58-60° C. (E;                                                      E)     I.288        (CH.sub.2).sub.5 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 76-78° C. (E;                                                      E)     I.289        (CH.sub.2).sub.5 CH.sub.3                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 78-80° C. (E;                                                      E)     I.290        CH.sub.2 C.sub.6 H.sub.5                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 85-88° C. (E;                                                      E)     I.291        CH.sub.2 C.sub.6 H.sub.5                          2-CH.sub.3                                H   4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 98-101° C.                                                      (E; E)     I.292        CH.sub.3          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 86-89° C. (E;                                                      E)     I.293        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH resin (E; E)     I.294        CH(CH.sub.3).sub.2                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 83-88° C. (E;                                                      E)     I.295        CH(CH.sub.3).sub.2                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 90-92° C. (E;                                                      E)     I.296        (CH.sub.2).sub.3 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH mp: 50-52° C. (E;                                                      E)     I.297        CH.sub.2 C.sub.6 H.sub.5                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH resin (E; E)     I.298        CH.sub.2 C.sub.6 H.sub.5                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 41-43° C. (E;                                                      E)     I.299        CH.sub.3          3-C(CH.sub.3).sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH resin (E; E)     I.300        CH.sub.3          3-C(CH.sub.3).sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   N  mp: 82-86° C. (E;                                                      E)     I.301        CH.sub.3          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   CH mp: 65-67°C. (E;                                                      E)     I.302        CH.sub.2 CHCH.sub.2                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   CH mp: 83-86° C. (E;                                                      E)     I.303        CH(C.sub.3).sub.2 2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   CH mp: 92-94° C. (E;                                                      E)     I.304        CH(CH.sub.3).sub.2                          2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   N  mp: 96-98° C. (E;                                                      E)     I.305        CH.sub.3          2-CH.sub.3                                H   4 (CH.sub.2).sub.2 CH.sub.3                                            OCH.sub.3                                                   CH mp: 50-52° C. (E;                                                      E)     I.306        CH.sub.3          2-CH.sub.3                                H   4 CH(CH.sub.3).sub.2                                            OCH.sub.3                                                   N  mp: 73-75° C. (E;                                                      E)     I.307        C.sub.2 H.sub.5   2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH resin (E; E)     I.308        C.sub.2 H.sub.5   2-CH.sub.3                                H   4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   CH mp: 52-55° C. (E;                                                      E)     I.309        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 CH.sub.3                                            OCH.sub.3                                                   CH resin (E; E)     I.310        (CH.sub.2).sub.2 CH.sub.3                          2-CH.sub.3                                5-CH.sub.3                                    4 C.sub.2 H.sub.5                                            OCH.sub.3                                                   CH mp: 85-87° C. (E;                                                      E)     __________________________________________________________________________      P° = position of the group CR.sup.4NOR.sup.1 relative to the      OCH.sub.2 bridge      cC.sub.3 H.sub.5 = cyclopropyl

    ______________________________________     Table 1:            Compounds of the general formula I.1, in which the            combination of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4            and X            for a compound corresponds to a line in Table A      ##STR6##     Table 2:            Compounds of the general formula I.2, in which the            combination of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4            and X            for a compound corresponds to a line in Table B      ##STR7##     Table 3:            Compounds of the general formula I.3, in which the            combination of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4            and X            for a compound corresponds to a line in Table A      ##STR8##     Table 4:            Compounds of the general formula I.4, in which the            combination of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4            and X            for a compound corresponds to a line in Table B      ##STR9##     Table 5:            Compounds of the general formula I.5, in which the            combination of the substituents R.sup.1, R.sup.2, R.sup.3,            R.sup.4, R.sup.5, R.sup.6            and X for a compound corresponds to a line in Table C      ##STR10##     Table 6:            Compounds of the general formula I.2, in which R.sup.4 is            cyclopropyl and the combination of the substituents            R.sup.1, R.sup.2, R.sup.3 and X for a compound corresponds to a            line            in Table D     Table 7:            Compounds of the general formula I.2, in which R.sup.4 is            cyclopentyl and the combination of the substituents            R.sup.1, R.sup.2, R.sup.3 and X for a compound corresponds to a            line            in Table D     Table 8:            Compounds of the general formula I.2, in which R.sup.4 is            cyclohexyl and the combination of the substituents            R.sup.1, R.sup.2, R.sup.3 and X for a compound corresponds to a            line            in Table D     Table 9:            Compounds of the general formula I.2, in which R.sup.4 is            CF.sub.3 and the combination of the substituents R.sup.1,            R.sup.2,            R.sup.3 and X for a compound corresponds to a line in            Table D     Table 10:            Compounds of the general formula I.2, in which R.sup.4 is            CH.sub.2 Cl and the combination of the substituents R.sup.1,            R.sup.2,            R.sup.3 and X for a compound corresponds to a line in            Table D     Table 11:            Compounds of the general formula I.2, in which R.sup.4 is            CH.sub.2 CH.sub.2 Cl and the combination of the substituents            R.sup.1,            R.sup.2, R.sup.3 and X for a compound corresponds to a line in            Table D     Table 12:            Compounds of the general formula I.4, in which R.sup.4 is            cyclopropyl and the combination of the substituents            R.sup.1, R.sup.2, R.sup.3 and X for a compound corresponds to a            line            in Table D     Table 13:            Compounds of the general formula I.4, in which R.sup.4 is            cyclopentyl and the combination of the substituents            R.sup.1, R.sup.2, R.sup.3 and X for a compound corresponds to a            line            in Table D     Table 14:            Compounds of the general formula I.4, in which R.sup.4 is            cyclohexyl and the combination of the substituents            R.sup.1, R.sup.2, R.sup.3 and X for a compound corresponds to a            line            in Table D     Table 15:            Compounds of the general formula I.4, in which R.sup.4 is            CF.sub.3 and the combination of the substituents R.sup.1, R.sup.2,            R.sup.3            and X for a compound corresponds to a line in Table D     Table 16:            Compounds of the general formula I.4, in which R.sup.4 is            CH.sub.2 Cl and the combination of the substituents R.sup.1,            R.sup.2,            R.sup.3 and X for a compound corresponds to a line in            Table D     Table 17:            Compounds of the general formula I.4, in which R.sup.4 is            CH.sub.2 CH.sub.2 Cl and the combination of the substituents            R.sup.1,            R.sup.2, R.sup.3 and X for a compound corresponds to a line in            Table D     Table 18:            Compounds of the general formula I.2, in which R.sup.4 is            cyclopropyl, =X- is =N- and the combination of the            substituents R.sup.1, R.sup.2 and R.sup.3 for a compound            corresponds            to a line in Table E     Table 19:            Compounds of the general formula I.2, in which R.sup.4 is            cyclopentyl, X is N and the combination of the            substituents R.sup.1, R.sup.2 and R.sup.3 for a compound            corresponds            to a line in Table E     Table 20:            Compounds of the general formula I.2, in which R.sup.4 is            cyclohexyl, X is N and the combination of the            substituents R.sup.1, R.sup.2 and R.sup.3 for a compound            corresponds            to a line in Table E     Table 21:            Compounds of the general formula I.2, in which R.sup.4 is            CF.sub.3, X is N and the combination of the substitu-            ents R.sup.1, R.sup.2 and R.sup.3 for a compound corresponds to a            line in Table E     Table 22:            Compounds of the general formula I.2, in which R.sup.4 is            CH.sub.2 CH.sub.2 Cl, X is N and the combination of the sub-            stituents R.sup.1, R.sup.2 and R.sup.3 for a compound corresponds            to            a line in Table E     Table 23:            Compounds of the general formula I.4, in which R.sup.4 is            cyclopropyl, X is N and the combination of the            substituents R.sup.1, R.sup.2 and R.sup.3 for a compound            corresponds            to a line in Table E     Table 24:            Compounds of the general formula I.4, in which R.sup.4 is            cyclopentyl, X is N and the combination of the            substituents R.sup.1, R.sup.2 and R.sup.3 for a compound            corresponds            to a line in Table E     Table 25:            Compounds of the general formula I.4, in which R.sup.4 is            cyclohexyl, X is N and the combination of the            substituents R.sup.1, R.sup.2 and R.sup.3 for a compound            corresponds            to a line in Table E     Table 26:            Compounds of the general formula I.4, in which R.sup.4 is            CF.sub.3, X is N and the combination of the substitu-            ents R.sup.1, R.sup.2 and R.sup.3 for a compound corresponds to a            line in Table E     Table 27:            Compounds of the general formula I.4, in which R.sup.4 is            CH.sub.2 CH.sub.2 Cl, X is N and the combination of the sub-            stituents R.sup.1, R.sup.2 and R.sup.3 for a compound corresponds            to            a line in Table E     ______________________________________

                                      TABLE A     __________________________________________________________________________     Comp. no.            R.sup.1            R.sup.2                                    R.sup.3                                       R.sup.4                                          X     __________________________________________________________________________     A.001  CH.sub.3 --        H    H  H  CH     A.002  CH.sub.3 --        H    H  H  N     A.003  CH.sub.3 --        2-Cl 5-Cl                                       H  CH     A.004  CH.sub.3 --        2-Cl 5-Cl                                       H  N     A.005  CH.sub.3 --        4-Cl H  H  CH     A.006  CH.sub.3 --        4-Cl H  H  N     A.007  CH.sub.3 --        4-CH.sub.3                                    H  H  CH     A.008  CH.sub.3 --        4-CH.sub.3                                    H  H  N     A.009  CH.sub.3 --        5-OCH.sub.3                                    H  H  CH     A.010  CH.sub.3 --        5-OCH.sub.3                                    H  H  N     A.011  CH.sub.3 --        6-OCH.sub.3                                    H  H  CH     A.012  CH.sub.3 --        6-OCH.sub.3                                    H  H  N     A.013  CH.sub.3 --        H    H  H  CH     A.014  CH.sub.3 --CH.sub.2 --                               H    H  H  N     A.015  CH.sub.3 --CH.sub.2 --                               2-Cl 5-Cl                                       H  CH     A.016  CH.sub.3 --CH.sub.2 --                               2-Cl 5-Cl                                       H  N     A.017  CH.sub.3 --CH.sub.2 --                               4-Cl H  H  CH     A.018  CH.sub.3 --CH.sub.2 --                               4-Cl H  H  N     A.019  CH.sub.3 --CH.sub.2 --                               4-CH.sub.3                                    H  H  CH     A.020  CH.sub.3 --CH.sub.2 --                               4-CH.sub.3                                    H  H  N     A.021  CH.sub.3 --CH.sub.2 --                               5-OCH.sub.3                                    H  H  CH     A.022  CH.sub.3 --CH.sub.2 --                               5-OCH.sub.3                                    H  H  N     A.023  CH.sub.3 --CH.sub.2 --                               6-OCH.sub.3                                    H  H  CH     A.024  CH.sub.3 --CH.sub.2 --                               6-OCH.sub.3                                    H  H  N     A.025  CH.sub.3 --CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.026  CH.sub.3 --CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.027  CH.sub.2 ═CH--CH.sub.2 --                               H    H  H  CH     A.028  CH.sub.2 ═CH--CH.sub.2 --                               H    H  H  N     A.029  CH.sub.3 --CH (CH.sub.3)--                               H    H  H  CH     A.030  CH.sub.3 --CH (CH.sub.3)--                               H    H  H  N     A.031  HC.tbd.C--CH.sub.2 --                               H    H  H  CH     A.032  HC═C--CH.sub.2 --                               H    H  H  N     A.033  cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                               H    H  H  CH     A.034  cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                               H    H  H  N     A.035  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.036  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.037  CH.sub.3 --CH═CH--CH.sub.2 --                               H    H  H  CH     A.038  CH.sub.3 --CH=CH--CH.sub.2 --                               H    H  H  N     A.039  CH.sub.3 --(CH.sub.2).sub.5 --                               H    H  H  CH     A.040  CH.sub.3 --(CH.sub.2).sub.5 --                               H    H  H  N     A.041  cyclo-C.sub.6 H.sub.11 --                               H    H  H  CH     A.042  cyclo-C.sub.6 H.sub.11 --                               H    H  H  N     A.043  C.sub.6 H.sub.5 --CH.sub.2 --                               H    H  H  CH     A.044  C.sub.6 H.sub.5 --CH.sub.2 --                               H    H  H  N     A.045  4-Cl-C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  CH     A.046  4-Cl-C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  N     A.047  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  CH     A.048  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  N     A.049  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.050  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.051  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.052  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.053  C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                               H    H  H  CH     A.054  C.sub.6 H.sub.5 --(CH.sub.).sub.4 --                               H    H  H  N     A.055  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                               H    H  H  CH     A.056  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                               H    H  H  N     A.057  4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.058  4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.059  t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                               H    H  H  CH     A.060  t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                               H    H  H  N     A.061  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.2 --                               H    H  H  CH     A.062  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.2 --                               H    H  H  N     A.063  Cl--CH═CH--CH.sub.2 --                               H    H  H  CH     A.064  Cl--CH═CH--CH.sub.2 --                               H    H  H  N     A.065  C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                    H  H  CH     A.066  C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                    H  H  N     A.067  CH.sub.3 --C(CH.sub.3).sub.2 --                               H    H  H  CH     A.068  CH.sub.3 --C(CH.sub.3).sub.2 --                               H    H  H  N     A.069  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                               H    H  H  CH     A.070  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                               H    H  H  N     A.071  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                               H    H  H  CH     A.072  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                               H    H  H  N     A.073  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.074  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.075  CH.sub.3 --(CH.sub.2).sub.4 --                               H    H  H  CH     A.076  CH.sub.3 --CH.sub.2).sub.4 --                               H    H  H  N     A.077  2-F--C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  CH     A.078  2-F--C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  N     A.079  3-F--C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  CH     A.080  3-F--C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  N     A.081  2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  CH     A.082  2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                               H    H  H  N     A.083  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                               H    H  H  CH     A.084  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                               H    H  H  N     A.085  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                               H    H  H  CH     A.086  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                               H    H  H  N     A.087  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.088  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.089  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                               H    H  H  CH     A.090  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                               H    H  H  N     A.091  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2 --                               H    H  H     A.092  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2 --                               H    H  H     A.093  4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                               H-   H  H  CH     A.094  4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                               H-   H  H  N     A.095  CH.sub.3           H    H  CH.sub.3                                          CH     A.096  CH.sub.3           H    H  CH.sub.3                                          N     A.097  CH.sub.3           2-Cl 5-Cl                                       CH.sub.3                                          CH     A.098  CH.sub.3           2-Cl 5-Cl                                       CH.sub.3                                          N     A.099  CH.sub.3           4-Cl H  CH.sub.3                                          CH     A.100  CH.sub.3           4-Cl H  CH.sub.3                                          N     A.101  CH.sub.3           4-CH.sub.3                                    H  CH.sub.3                                          CH     A.102  CH.sub.3           4-CH.sub.3                                    H  CH.sub.3                                          N     A.103  CH.sub.3           5-OCH.sub.3                                    H  CH.sub.3                                          CH     A.104  CH.sub.3           5-OCH.sub.3                                    H  CH.sub.3                                          N     A.105  CH.sub.3           6-OCH.sub.3                                    H  CH.sub.3                                          CH     A.106  CH.sub.3           6-OCH.sub.3                                    H  CH.sub.3                                          N     A.107  CH.sub.3 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.108  CH.sub.3 --CH.sub.2                               H    H  CH.sub.3                                          N     A.109  CH.sub.3 --CH.sub.2                               2-Cl 5-Cl                                       CH.sub.3                                          CH     A.110  CH.sub.3 --CH.sub.2                               2-Cl 5-Cl                                       CH.sub.3                                          N     A.111  CH.sub.3 --CH.sub.2                               4-Cl H  CH.sub.3                                          CH     A.112  CH.sub.3 --CH.sub.2                               4-Cl H  CH.sub.3                                          N     A.113  CH.sub.3 --CH.sub.2                               4-CH.sub.3                                    H  CH.sub.3                                          CH     A.114  CH.sub.3 --CH.sub.2                               4-CH.sub.3                                    H  CH.sub.3                                          N     A.115  CH.sub.3 --CH.sub.2                               5-OCH.sub.3                                    H  CH.sub.3                                          CH     A.116  CH.sub.3 --CH.sub.2                               5-OCH.sub.3                                    H  CH.sub.3                                          N     A.117  CH.sub.3 --CH.sub.2                               6-OCH.sub.3                                    H  CH.sub.3                                          CH     A.118  CH.sub.3 --CH.sub.2                               6-OCH.sub.3                                    H  CH.sub.3                                          N     A.119  CH.sub.3 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.120  CH.sub.3 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.121  CH.sub.2 ═CH--CH.sub.2                               H    H  CH.sub.3                                          CH     A.122  CH.sub.2 ═CH--CH.sub.2                               H    H  CH.sub.3                                          N     A.123  CH.sub.3 --CH(CH.sub.3)                               H    H  CH.sub.3                                          CH     A.124  CH.sub.3 --CH(CH.sub.3)                               H    H  CH.sub.3                                          N     A.125  HC.tbd.C--CH.sub.2 H    H  CH.sub.3                                          CH     A.126  HC.tbd.C--CH.sub.2 H    H  CH.sub.3                                          wN     A.127  cyclo-C.sub.3 H.sub.5 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.128  cyclo-C.sub.3 H.sub.5 --CH.sub.2                               H    H  CH.sub.3                                          N     A.129  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.130  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.131  CH.sub.3 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          CH     A.132  CH.sub.3 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          N     A.133  CH.sub.3 --(CH.sub.2).sub.5                               H    H  CH.sub.3                                          CH     A.134  CH.sub.3 --(CH.sub.2).sub.5                               H    H  CH.sub.3                                          N     A.135  cyclo-C.sub.6 H.sub.11                               H    H  CH.sub.3                                          CH     A.136  cyclo-C.sub.6 H.sub.11                               H    H  CH.sub.3                                          N     A.137  C.sub.6 H.sub.5 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.138  C.sub.6 H.sub.5 --CH.sub.2                               H    H  CH.sub.3                                          N     A.139  4-Cl--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.140  4-Cl--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          N     A.141  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.142  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          N     A.143  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.144  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.145  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.146  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.147  C.sub.6 H.sub.5 --(CH.sub.2).sub.4                               H    H  CH.sub.3                                          CH     A.148  C.sub.6 H.sub.5 --(CH.sub.2).sub.4                               H    H  CH.sub.3                                          N     A.149  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          CH     A.150  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          N     A.151  4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.152  4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.153  t-C.sub.4 H.sub.9 O--CO--CH.sub.2                               H    H  CH.sub.3                                          CH     A.154  t-C.sub.4 H.sub.9 O--CO--CH.sub.2                               H    H  CH.sub.3                                          N     A.155  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3                               H    H  CH.sub.3                                          CH     A.156  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3                               H    H  CH.sub.3                                          N     A.157  Cl--CH═CH--CH.sub.2                               H    H  CH.sub.3                                          CH     A.158  Cl--CH═CH--CH.sub.2                               H    H  CH.sub.3                                          N     A.159  C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                    H  CH.sub.3                                          CH     A.160  C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                    H  CH.sub.3                                          N     A.161  CH.sub.3 --C(CH.sub.2).sub.2                               H    H  CH.sub.3                                          CH     A.162  CH.sub.3 --C(CH.sub.2).sub.2                               H    H  CH.sub.3                                          N     A.163  CH.sub.3 --CH(CH.sub.3)--CH.sub.2                               H    H  CH.sub.3                                          CH     A.164  CH.sub.3 --CH(CH.sub.3)--CH.sub.2                               H    H  CH.sub.3                                          N     A.165  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                               H    H  CH.sub.3                                          CH     A.166  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                               H    H  CH.sub.3                                          N     A.167  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.168  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.169  CH.sub.3 --(CH.sub.2).sub.4                               H    H  CH.sub.3                                          CH     A.170  CH.sub.3 --(CH.sub.2).sub.4                               H    H  CH.sub.3                                          N     A.171  2-F--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.172  2-F--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          N     A.173  3-F--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.174  3-F--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          N     A.175  2-Cl--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.176  2-Cl--C.sub.6 H.sub.4 --CH.sub.2                               H    H  CH.sub.3                                          N     A.177  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.178  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                               H    H  CH.sub.3                                          N     A.179  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.180  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                               H    H  CH.sub.3                                          N     A.181  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.182  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                               H    H  H3 N     A.183  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          CH     A.184  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                               H    H  CH.sub.3                                          N     A.185  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          CH     A.186  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          N     A.187  4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          CH     A.188  4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                               H    H  CH.sub.3                                          N     A.189  CH.sub.3           H    H  C.sub.6 H.sub.5                                          CH     A.190  CH.sub.3           H    H  C.sub.6 H.sub.5                                          N     A.191  C.sub.2 H.sub.5    H    H  C.sub.6 H.sub.5                                          CH     A.192  C.sub.2 H.sub.5    H    H  C.sub.6 H.sub.5                                          N     A.193  CH.sub.3 --CH.sub.2 --CH.sub.2                               H    H  C.sub.6 H.sub.5                                          CH     A.194  CH.sub.3 --CH.sub.2 --CH.sub.2                               H    H  C.sub.6 H.sub.5                                          N     A.195  CH.sub.3 --(CH.sub.2).sub.5                               H    H  C.sub.6 H.sub.5                                          CH     A.196  CH.sub.3 --(CH.sub.2).sub.5                               H    H  C.sub.6 H.sub.5                                          N     A.197  C.sub.6 H.sub.5 --CH.sub.2                               H    H  C.sub.6 H.sub.5                                          CH     A.198  C.sub.6 H.sub.5 --CH.sub.2                               H    H  C.sub.6 H.sub.5                                          N     __________________________________________________________________________

                                      TABLE B     __________________________________________________________________________     Comp. no.            R.sup.1         R.sup.2  R.sup.3 R.sup.4   X     __________________________________________________________________________     B.001  CH.sub.3 --     H        H       H         CH     B.002  CH.sub.3 --     H        H       H         N     B.003  CH.sub.3 --     2-Cl     H       H         CH     B.004  CH.sub.3 --     2-Cl     H       H         N     B.005  CH.sub.3 --     2-CH.sub.3                                     H       H         CH     B.006  CH.sub.3 --     2-CH.sub.3                                     H       H         N     B.007  CH.sub.3 --     2-OCH.sub.3                                     H       H         CH     B.008  CH.sub.3 --     2-OCH.sub.3                                     H       H         N     B.009  CH.sub.3 --     3-Cl     H       H         CH     B.010  CH.sub.3 --     3-Cl     H       H         N     B.011  CH.sub.3 --     3-CH.sub.3                                     H       H         CH     B.012  CH.sub.3 --     3-CH.sub.3                                     H       H         N     B.013  CH.sub.3 --     3-OCH.sub.3                                     H       H         CH     B.014  CH.sub.3 --     3-OCH.sub.3                                     H       H         N     B.015  CH.sub.3        2-Cl     6-Cl    H         CH     B.016  CH.sub.3        2-Cl     6-Cl    H         N     B.017  CH.sub.3 --CH.sub.2 --                            H        H       H         CH     B.018  CH.sub.3 --CH.sub.2 --                            H        H       H         N     B.019  CH.sub.3 --CH.sub.2 --                            2-Cl     H       H         CH     B.020  CH.sub.3 --CH.sub.2 --                            2-Cl     H       H         N     B.021  CH.sub.3 --CH.sub.2 --                            2-CH.sub.3                                     H       H         CH     B.022  CH.sub.3 --CH.sub.2 --                            2-CH.sub.3                                     H       H         N     B.023  CH.sub.3 --CH.sub.2 --                            2-OCH.sub.3                                     H       H         CH     B.024  CH.sub.3 --CH.sub.2 --                            2-OCH.sub.3                                     H       H         N     B.025  CH.sub.3 --CH.sub.2 --                            3-Cl     H       H         CH     B.026  CH.sub.3 --CH.sub.2 --                            3-Cl     H       H         N     B.027  CH.sub.3 --CH.sub.2 --                            3-CH.sub.3                                     H       H         CH     B.028  CH.sub.3 --CH.sub.2 --                            3-CH.sub.3                                     H       H         N     B.029  CH.sub.3 --CH.sub.2 --                            3-OCH.sub.3                                     H       H         CH     B.030  CH.sub.3 --CH.sub.2 --                            3-OCH.sub.3                                     H       H         N     B.031  CH.sub.3 --CH.sub.2 --                            2-Cl     H       H         CH     B.032  CH.sub.3 --CH.sub.2 --                            2-Cl     6-Cl    H         N     B.033  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            H        6-Cl    H         CH     B.034  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            H        H       H         N     B.035  CH.sub.2 ═CH--CH.sub.2 --                            H        H       H         CH     B.036  CH.sub.2 ═CH--CH.sub.2 --                            H        H       H         N     B.037  CH.sub.3 --CH(CH.sub.3)--                            H        H       H         CH     B.038  CH.sub.3 --CH(CH.sub.3)--                            H        H       H         N     B.039  HC.tbd.C--CH.sub.2 --                            H        H       H         CH     B.040  HC.tbd.C--CH.sub.2 --                            H        H       H         N     B.041  cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                            H        H       H         CH     B.042  cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                            H        H       H         N     B.043  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                            H        H       H         CH     B.044  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                            H        H       H         N     B.045  CH.sub.3 --CH═CH--CH.sub.2 --                            H        H       H         CH     B.046  CH.sub.3 --CH═CH--CH.sub.2 --                            H        H       H         N     B.047  CH.sub.3 --(CH.sub.2).sub.5 --                            H        H       H         CH     B.048  CH.sub.3 --(CH.sub.2).sub.5 --                            H        H       H         N     B.049  cyclo-C.sub.6 H.sub.11 --                            H        H       H         CH     B.050  cyclo-C.sub.6 H.sub.11 --                            H        H       H         N     B.051  C.sub.6 H.sub.5 --CH.sub.2 --                            H        H       H         CH     B.052  C.sub.6 H.sub.5 --CH.sub.2 --                            H        H       H         N     B.053  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         CH     B.054  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         N     B.055  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         CH     B.056  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         N     B.057  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         CH     B.058  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         N     B.059  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                            H        H       H         CH     B.060  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                            H        H       H         N     B.061  C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                            H        H       H         CH     B.062  C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                            H        H       H         N     B.063  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                            H        H       H         CH     B.064  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                            H        H       H         N     B.065  4-F--C.sub.6 H.sub.4 --                            H        H       H         CH            CH═CHCH.sub.2 CH.sub.2     B.066  4-F--C.sub.6 H.sub.4 --                            H        H       H         N            CH═CHCH.sub.2 CH.sub.2     B.067  t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                            H        H       H         CH     B.068  t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                            H        H       H         N     B.069  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                            H        H       H         CH     B.070  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                            H        H       H         N     B.071  Cl--CH═CH--CH.sub.2 --                            H        H       H         CH     B.072  Cl--CH═CH--CH.sub.2 --                            H        H       H         N     B.073  C.sub.2 H.sub.5 6-OC.sub.2 H.sub.5                                     H       H         CH     B.074  C.sub.2 H.sub.5 6-OC.sub.2 H.sub.5                                     H       H         N     B.075  CH.sub.3 --C(CH.sub.3).sub.2 --                            H        H       H         CH     B.076  CH.sub.3 --C(CH.sub.3).sub.2 --                            H        H       H         N     B.077  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                            H        H       H         CH     B.078  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                            H        H       H         N     B.079  CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                            H        H       H         CH     B.080  CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                            H        H       H         N     B.081  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                            H        H       H         CH     B.082  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                            H        H       H         N     B.083  CH.sub.3 --(CH.sub.2).sub.4 --                            H        H       H         CH     B.084  CH.sub.3 --(CH.sub.2).sub.4 --                            H        H       H         N     B.085  2-F--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         CH     B.086  2-F--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         N     B.087  3-F--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         CH     B.088  3-F--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         N     B.089  2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         CH     B.090  2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                            H        H       H         N     B.091  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                            H        H       H         CH     B.092  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                            H        H       H         N     B.093  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                            H        H       H         CH     B.094  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                            H        H       H         N     B.095  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                            H        H       H         CH     B.096  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                            H        H       H         N     B.097  C.sub.6 H.sub.5 --CH═CH--                            H        H       H         CH            CH.sub.2 --CH.sub.2 --     B.098  C.sub.6 H.sub.5 --CH═CH--                            H        H       H         N            CH.sub.2 --CH.sub.2 --     B.099  4-Cl--C.sub.6 H.sub.4 --                            H        H       H         CH            CH.sub.2 CH═CHCH.sub.2     B.100  4-Cl--C.sub.6 H.sub.4 --                            H        H       H         N            CH.sub.2 CH═CHCH.sub.2     B.101  4-CF.sub.3 --C.sub.6 H.sub.4 --                            H        H       H         CH            CH.sub.2 CH═CHCH.sub.2     B.102  4-CF.sub.3 --C.sub.6 H.sub.4 --                            H        H       H         N            CH.sub.2 CH═CHCH.sub.2     B.103  CH.sub.3        H        H       CH.sub.3  CH     B.104  CH.sub.3        H        H       CH.sub.3  N     B.105  CH.sub.3        2-Cl     H       CH.sub.3  CH     B.106  CH.sub.3        2-Cl     H       CH.sub.3  N     B.107  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3  CH     B.108  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3  N     B.109  CH.sub.3        2-OCH.sub.3                                     H       CH.sub.3  CH     B.110  CH.sub.3        2-OCH.sub.3                                     H       CH.sub.3  N     B.111  CH.sub.3        3-Cl     H       CH.sub.3  CH     B.112  CH.sub.3        3-Cl     H       CH.sub.3  N     B.113  CH.sub.3        3-CH.sub.3                                     H       CH.sub.3  CH     B.114  CH.sub.3        3-CH.sub.3                                     H       CH.sub.3  N     B.115  CH.sub.3        3-OCH.sub.3                                     H       CH.sub.3  CH     B.116  CH.sub.3        3-OCH.sub.3                                     H       CH.sub.3  N     B.117  CH.sub.3        2-Cl     6-Cl    CH.sub.3  CH     B.118  CH.sub.3        2-Cl     6-Cl    CH.sub.3  N     B.119  CH.sub.3 --CH.sub.2                            H        H       CH.sub.3  CH     B.120  CH.sub.3 --CH.sub.2                            H        H       CH.sub.3  N     B.121  CH.sub.3 --CH.sub.2                            2-Cl     H       CH.sub.3  CH     B.122  CH.sub.3 --CH.sub.2                            2-Cl     H       CH.sub.3  N     B.123  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.124  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.125  CH.sub.3 --CH.sub.2                            2-OCH.sub.3                                     H       CH.sub.3  CH     B.126  CH.sub.3 --CH.sub.2                            2-OCH.sub.3                                     H       CH.sub.3  N     B.127  CH.sub.3 --CH.sub.2                            3-Cl     H       CH.sub.3  CH     B.128  CH.sub.3 --CH.sub.2                            3-Cl     H       CH.sub.3  N     B.129  CH.sub.3 --CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3  CH     B.130  CH.sub.3 --CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3  N     B.131  CH.sub.3 --CH.sub.2                            3-OCH.sub.3                                     H       CH.sub.3  CH     B.132  CH.sub.3 --CH.sub.2                            3-OCH.sub.3                                     H       CH.sub.3  N     B.133  CH.sub.3 --CH.sub.2                            2-Cl     6-Cl    CH.sub.3  CH     B.134  CH.sub.3 --CH.sub.2                            2-Cl     6-Cl    CH.sub.3  N     B.135  CH.sub.3 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.136  CH.sub.3 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.137  CH.sub.2 ═CH--CH.sub.2                            H        H       CH.sub.3  CH     B.138  CH.sub.2 ═CH--CH.sub.2                            H        H       CH.sub.3  N     B.139  CH.sub.3 --CH(CH.sub.3)                            H        H       CH.sub.3  CH     B.140  CH.sub.3 --CH(CH.sub.3)                            H        H       CH.sub.3  N     B.141  HC.tbd.C--CH.sub.2                            H        H       CH.sub.3  CH     B.142  HC.tbd.C--CH.sub.2                            H        H       CH.sub.3  N     B.143  cyclo-C.sub.3 H.sub.5 --CH.sub.2                            H        H       CH.sub.3  CH     B.144  cyclo-C.sub.3 H.sub.5 --CH.sub.2                            H        H       CH.sub.3  N     B.145  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.146  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.147  CH.sub.3 --CH═CH--CH.sub.2                            H        H       CH.sub.3  CH     B.148  CH.sub.3 --CH═CH--CH.sub.2                            H        H       CH.sub.3  N     B.149  CH.sub.3 --(CH.sub.2).sub.5                            H        H       CH.sub.3  CH     B.150  CH.sub.3 --(CH.sub.2).sub.5                            H        H       CH.sub.3  N     B.151  cyclo-C.sub.6 H.sub.11                            H        H       CH.sub.3  CH     B.152  cyclo-C.sub.6 H.sub.11                            H        H       CH.sub.3  N     B.153  C.sub.6 H.sub.5 --CH.sub.2                            H        H       CH.sub.3  CH     B.154  C.sub.6 H.sub.5 --CH.sub.2                            H        H       CH.sub.3  N     B.155  4-Cl--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  CH     B.156  4-Cl--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  N     B.157  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  CH     B.158  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  N     B.159  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.160  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.161  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.162  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.163  C.sub.6 H.sub.5 --(CH.sub.2).sub.4                            H        H       CH.sub.3  CH     B.164  C.sub.6 H.sub.5 --(CH.sub.2).sub.4                            H        H       CH.sub.3  N     B.165  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                            H        H       CH.sub.3  CH     B.166  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                            H        H       CH.sub.3  N     B.167  4-F--C.sub.6 H.sub.4 --CH═--CHCH.sub.2                            H        H       CH.sub.3  CH     B.168  4-F--C.sub.6 H.sub.4 --CH═--CHCH.sub.2                            H        H       CH.sub.3  N     B.169  t-C.sub.4 --H.sub.9 O--CO--CH.sub.2                            H        H       CH.sub.3  CH     B.170  t-C.sub.4 --H.sub.9 O--CO--CH.sub.2                            H        H       CH.sub.3  N     B.171  t-C.sub.4 --H.sub.9 O--CO--(CH.sub.2).sub.3                            H        H       CH.sub.3  CH     B.172  t-C.sub.4 --H.sub.9 O--CO--(CH.sub.2).sub.3                            H        H       CH.sub.3  N     B.173  Cl--CH═CH--CH.sub.2                            H        H       CH.sub.3  CH     B.174  Cl--CH═CH--CH.sub.2                            H        H       CH.sub.3  N     B.175  C.sub.2 H.sub.5 6-OC.sub.2 H.sub.5                                     H       CH.sub.3  CH     B.176  C.sub.2 H.sub.5 6-OC.sub.2 H.sub.5                                     H       CH.sub.3  N     B.177  CH.sub.3 --C(CH.sub.3).sub.2                            H        H       CH.sub.3  CH     B.178  CH.sub.3 --C(CH.sub.3).sub.2                            H        H       CH.sub.3  N     B.179  CH.sub.3 --CH(CH.sub.3)--CH.sub.2                            H        H       CH.sub.3  CH     B.180  CH.sub.3 --CH(CH.sub.3)--CH.sub.2                            H        H       CH.sub.3  N     B.181  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                            H        H       CH.sub.3  CH     B.182  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                            H        H       CH.sub.3  N     B.183  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                            H        H       CH.sub.3  CH     B.184  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                            H        H       CH.sub.3  N     B.185  CH.sub.3 --(CH.sub.2).sub.4                            H        H       CH.sub.3  CH     B.186  CH.sub.3 --(CH.sub.2).sub.4                            H        H       CH.sub.3  N     B.187  2-F--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  CH     B.188  2-F--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  N     B.189  3-F--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  CH     B.190  3-F--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  N     B.191  2-Cl--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  CH     B.192  2-Cl--C.sub.6 H.sub.4 --CH.sub.2                            H        H       CH.sub.3  N     B.193  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                            H        H       CH.sub.3  CH     B.194  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                            H        H       CH.sub.3  N     B.195  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                            H        H       CH.sub.3  CH     B.196  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                            H        H       CH.sub.3  N     B.197  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.198  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.199  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.200  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.201  4-Cl--C.sub.6 H.sub.4 --                            H        H       CH.sub.3  CH            CH.sub.2 --CH═CH--CH.sub.2     B.202  4-Cl--C.sub.6 H.sub.4 --                            H        H       CH.sub.3  N            CH.sub.2 --CH═CH--CH.sub.2     B.203  4-CF.sub.3 --C.sub.6 H.sub.4 --                            H        H       CH.sub.3  CH            CH.sub.2 --CH═CH--CH.sub.2     B.204  4-CF.sub.3 --C.sub.6 H.sub.4 --                            H        H       CH.sub.3  N            CH.sub.2 --CH═CH--CH.sub.2     B.205  CH.sub.3        H        H       C.sub.6 H.sub.5                                                       CH     B.206  CH.sub.3        H        H       CH.sub.3  N     B.207  C.sub.2 H.sub.5 H        H       CH.sub.3  CH     B.208  C.sub.2 H.sub.5 H        H       CH.sub.3  N     B.209  CH.sub.3 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  CH     B.210  CH.sub.3 --CH.sub.2 --CH.sub.2                            H        H       CH.sub.3  N     B.211  CH.sub.3 --(CH.sub.2).sub.5                            H        H       CH.sub.3  CH     B.212  CH.sub.3 --(CH.sub.2).sub.5                            H        H       CH.sub.3  N     B.213  C.sub.6 H.sub.5 --CH.sub.2                            H        H       CH.sub.3  CH     B.214  C.sub.6 H.sub.5 --CH.sub.2                            H        H       CH.sub.3  N     B.215  CH.sub.3        2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.216  CH.sub.3        2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       N     B.217  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.218  C.sub.2 H.sub.5 2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.219  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.220  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.221  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.222  CH.sub.3 --CH(CH.sub.3)                            2-CH.sub.3                                     H       CH.sub.3  CH     B.223  CH.sub.3 --CH(CH.sub.3)                            2-CH.sub.3                                     H       CH.sub.3  N     B.224  CH.sub.3 --CH(CH.sub.3)--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.225  CH.sub.3 --CH(CH.sub.3)--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.226  CH.sub.3 --(CH.sub.2).sub.3                            2-CH.sub.3                                     H       CH.sub.3  CH     B.227  CH.sub.3 --(CH.sub.2).sub.3                            2-CH.sub.3                                     H       CH.sub.3  N     B.228  CH.sub.3 --C(CH.sub.3).sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.229  CH.sub.3 --C(CH.sub.3).sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.230  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.231  CH.sub.2 ═C(CH.sub.3)--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.232  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.233  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.234  CH.sub.3 --(CH.sub.2).sub.5                            2-CH.sub.3                                     H       CH.sub.3  CH     B.235  CH.sub.3 --(CH.sub.2).sub.5                            2-CH.sub.3                                     H       CH.sub.3  N     B.236  C.sub.6 H.sub.5 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  CH     B.237  C.sub.6 H.sub.5 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.238  CH.sub.3        2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.239  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.240  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.241  CH.sub.3 --CH(CH.sub.3)                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.242  CH.sub.3 --CH(CH.sub.3)                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.243  CH.sub.3 --(CH.sub.2).sub.3                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.244  CH.sub.3 --(CH.sub.2).sub.3                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.245  C.sub.6 H.sub.5 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.246  C.sub.6 H.sub.5 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.247  CH.sub.3        3-CH.sub.3 C(CH.sub.3).sub.2                                     H       CH.sub.3  CH     B.248  CH.sub.3        3-CH.sub.3 C(CH.sub.3).sub.2                                     H       CH.sub.3  N     B.249  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       CH     B.250  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       N     B.251  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       CH     B.252  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       N     B.253  CH.sub.3 --CH(CH.sub.3)                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       CH     B.254  CH.sub.3 --CH(CH.sub.3)                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       N     B.255  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       CH     B.256  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2                                                       N     B.257  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --CH.sub.2                                                       CH     B.258  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH(CH.sub.3)                                                       N     B.259  C.sub.2 H.sub.5 2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.260  C.sub.2 H.sub.5 2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       CH     B.261  C.sub.2 H.sub.5 2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       N     B.262  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.263  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.264  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       CH     B.265  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       N     B.266  CH.sub.3        2-Cl     H       CH.sub.3  CH     B.267  CH.sub.3        2-Cl     H       CH.sub.3  N     B.268  C.sub.2 H.sub.5 2-Cl     H       CH.sub.3  CH     B.269  C.sub.2 H.sub.5 2-Cl     H       CH.sub.3  N     B.270  CH.sub.3        2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.271  CH.sub.3        2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.272  C.sub.2 H.sub.5 2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.273  C.sub.2 H.sub.5 2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.274  CH.sub.3        2-Cl     5-Cl    CH.sub.3  CH     B.275  CH.sub.3        2-Cl     5-Cl    CH.sub.3  N     B.276  C.sub.2 H.sub.5 2-Cl     5-Cl    CH.sub.3  CH     B.277  C.sub.2 H.sub.5 2-Cl     5-Cl    CH.sub.3  N     B.278  CH.sub.3 --O--CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     H       CH.sub.3  N     B.279  CH.sub.3 --O--CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       N     B.280  CH.sub.3 --(CH.sub.2).sub.3                            2-CH.sub.3                                     H       C.sub.2 H.sub.5                                                       N     B.281  CH.sub.3 --O--CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.282  CH.sub.3        2-CH.sub.3                                     5-CH.sub.3                                             C.sub.2 H.sub.5                                                       N     B.283  C.sub.2 H.sub.5 2-CH.sub.3                                     5-CH.sub.3                                             C.sub.2 H.sub.5                                                       N     B.284  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             C.sub.2 H.sub.5                                                       N     B.285  CH.sub.2 ═CH--CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             C.sub.2 H.sub.5                                                       N     B.286  CH.sub.3 --O--CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH.sub.3                                             C.sub.2 H.sub.5                                                       N     B.287  CH.sub.3 --(CH.sub.2).sub.3                            2-CH.sub.3                                     5-CH.sub.3                                             C.sub.2 H.sub.5                                                       N     B.288  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-Cl     H       CH.sub.3  N     B.289  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-Cl     H       CH.sub.3  CH     B.290  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     H       CH.sub.3  N     B.291  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     H       CH.sub.3  CH     B.292  CH.sub.2 ═CH--CH.sub.2 --                            2-Cl     H       CH.sub.3  N     B.293  CH.sub.2 ═CH--CH.sub.2 --                            2-Cl     H       CH.sub.3  CH     B.294  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  N     B.295  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  CH     B.296  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     H       CH.sub.3  N     B.297  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     H       CH.sub.3  CH     B.298  CH.sub.2 ═CH--CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  N     B.299  CH.sub.2 ═CH--CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  CH     B.300  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            3-CH.sub.3                                     H       CH.sub.3  N     B.301  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            3-CH.sub.3                                     H       CH.sub.3  CH     B.302  CH.sub.3 --(CH.sub.2).sub.3 --                            3-CH.sub.3                                     H       CH.sub.3  N     B.303  CH.sub.3 --(CH.sub.2).sub.3 --                            3-CH.sub.3                                     H       CH.sub.3  CH     B.304  CH.sub.2 ═CH--CH.sub.2 --                            3-CH.sub.3                                     H       CH.sub.3  N     B.305  CH.sub.2 ═CH--CH.sub.2 --                            3-CH.sub.3                                     H       CH.sub.3  CH     B.306  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --CH.sub.2                                                       N     B.307  CH.sub.3        2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --CH.sub.2                                                       CH     B.308  CH.sub.3 --(CH.sub.2).sub.5 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.309  CH.sub.3 --(CH.sub.2).sub.5 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.310  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  N     B.311  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  CH     B.312  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.313  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.314  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.315  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.316  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  N     B.317  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  CH     B.318  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.319  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.320  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.321  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.322  N.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  N     B.323  N.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  CH     B.324  N.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.325  N.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.326  CH.sub.3        2-CH.sub.3                                     H       C.sub.6 H.sub.5                                                       N     B.327  CH.sub.3        2-CH.sub.3                                     H       C.sub.6 H.sub.5                                                       CH     B.328  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     H       C.sub.6 H.sub.5                                                       N     B.329  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     H       C.sub.6 H.sub.5                                                       CH     B.330  (CH.sub.3).sub.3 COCO--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  N     B.331  (CH.sub.3).sub.3 COCO--CH.sub.2 --                            2-CH.sub.3                                     H       CH.sub.3  CH     B.332  (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.3                            2-CH.sub.3                                     H       CH.sub.3  N     B.333  (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.3                            2-CH.sub.3                                     H       CH.sub.3  CH     B.334  (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.4                            2-CH.sub.3                                     H       CH.sub.3  N     B.335  (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.4                            2-CH.sub.3                                     H       CH.sub.3  CH     B.336  (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.5                            2-CH.sub.3                                     H       CH.sub.3  N     B.337  (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.5                            2-CH.sub.3                                     H       CH.sub.3  CH     B.338  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.339  CH.tbd.C--CH.sub.2 --                            2-CH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.340  CH.sub.3        2-F      H       CH.sub.3  N     B.341  CH.sub.3        2-F      H       CH.sub.3  CH     B.342  CH.sub.3 --CH.sub.2                            2-F      H       CH.sub.3  N     B.343  CH.sub.3 --CH.sub.2                            2-F      H       CH.sub.3  CH     B.344  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-F      H       CH.sub.3  N     B.345  CH.sub.3 --CH.sub.2 --CH.sub.2 --                            2-F      H       CH.sub.3  CH     B.346  CH.sub.3 --(CH.sub.2).sub.3 --                            2-F      H       CH.sub.3  N     B.347  CH.sub.3 --(CH.sub.2).sub.3 --                            2-F      H       CH.sub.3  CH     B.348  CH.sub.2 ═CH--CH.sub.2 --                            2-F      H       CH.sub.3  N     B.349  CH.sub.2 ═CH--CH.sub.2 --                            2-F      H       CH.sub.3  CH     B.350  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-F      H       CH.sub.3  N     B.351  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-F      H       CH.sub.3  CH     B.352  Cl--CH═CH--CH.sub.2 --                            2-F      H       CH.sub.3  N     B.353  Cl--CH═CH--CH.sub.2 --                            2-F      H       CH.sub.3  CH     B.354  CH.sub.3        2-F      H       CH.sub.3 --CH.sub.2 --                                                       N     B.355  CH.sub.3        2-F      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.356  CH.sub.3 --CH.sub.2                            2-F      H       CH.sub.3 --CH.sub.2 --                                                       N     B.357  CH.sub.3 --CH.sub.2                            2-F      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.358  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-F      H       CH.sub.3 --CH.sub.2 --                                                       N     B.359  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-F      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.360  CH.sub.3 --(CH.sub.2).sub.3 --                            2-F      H       CH.sub.3 --CH.sub.2 --                                                       N     B.361  CH.sub.3 --(CH.sub.2).sub.3 --                            2-F      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.362  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Cl     H       CH.sub.3  N     B.363  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Cl     H       CH.sub.3  CH     B.364  Cl--CH═CH--CH.sub.2                            2-Cl     H       CH.sub.3  N     B.365  Cl--CH═CH--CH.sub.2                            2-Cl     H       CH.sub.3  CH     B.366  CH.sub.3        2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       N     B.367  CH.sub.3        2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.368  CH.sub.3 --CH.sub.2 --                            2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       N     B.369  CH.sub.3 --CH.sub.2 --                            2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.370  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       N     B.371  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.372  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       N     B.373  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.374  CH.sub.3        2-Br     H       CH.sub.3  N     B.375  CH.sub.3        2-Br     H       CH.sub.3  CH     B.376  CH.sub.3 --CH.sub.2                            2-Br     H       CH.sub.3  N     B.377  CH.sub.3 --CH.sub.2                            2-Br     H       CH.sub.3  CH     B.378  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Br     H       CH.sub.3  N     B.379  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Br     H       CH.sub.3  CH     B.380  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Br     H       CH.sub.3  N     B.381  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Br     H       CH.sub.3  CH     B.382  CH.sub.2 ═CH--CH.sub.2 --                            2-Br     H       CH.sub.3  N     B.383  CH.sub.2 ═CH--CH.sub.2 --                            2-Br     H       CH.sub.3  CH     B.384  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Br     H       CH.sub.3  N     B.385  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Br     H       CH.sub.3  CH     B.386  Cl--CH═CH--CH.sub.2 --                            2-Br     H       CH.sub.3  N     B.387  Cl--CH═CH--CH.sub.2 --                            2-Br     H       CH.sub.3  CH     B.388  CH.sub.3        2-Br     H       CH.sub.3 --CH.sub.2 --                                                       N     B.389  CH.sub.3        2-Br     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.390  CH.sub.3 --CH.sub.2                            2-Br     H       CH.sub.3 --CH.sub.2 --                                                       N     B.391  CH.sub.3 --CH.sub.2                            2-Br     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.392  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Br     H       CH.sub.3 --CH.sub.2 --                                                       N     B.393  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Br     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.394  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Br     H       CH.sub.3 --CH.sub.2 --                                                       N     B.395  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Br     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.396  CH.sub.3        2-I      H       CH.sub.3  N     B.397  CH.sub.3        2-I      H       CH.sub.3  CH     B.398  CH.sub.3 --CH.sub.2 --                            2-I      H       CH.sub.3  N     B.399  CH.sub.3 --CH.sub.2 --                            2-I      H       CH.sub.3  CH     B.400  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-I      H       CH.sub.3  N     B.401  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-I      H       CH.sub.3  CH     B.402  CH.sub.3 --(CH.sub.2).sub.3 --                            2-I      H       CH.sub.3  N     B.403  CH.sub.3 --(CH.sub.2).sub.3 --                            2-I      H       CH.sub.3  CH     B.404  CH.sub.2 ═CH--CH.sub.2 --                            2-I      H       CH.sub.3  N     B.405  CH.sub.2 ═CH--CH.sub.2 --                            2-I      H       CH.sub.3  CH     B.406  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-I      H       CH.sub.3  N     B.407  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-I      H       CH.sub.3  CH     B.408  Cl--CH═CH--CH.sub.2 --                            2-I      H       CH.sub.3  N     B.409  Cl--CH═CH--CH.sub.2 --                            2-I      H       CH.sub.3  CH     B.410  CH.sub.3        2-I      H       CH.sub.3 --CH.sub.2 --                                                       N     B.411  CH.sub.3        2-I      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.412  CH.sub.3 --CH.sub.2                            2-I      H       CH.sub.3 --CH.sub.2 --                                                       N     B.413  CH.sub.3 --CH.sub.2                            2-I      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.414  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-I      H       CH.sub.3 --CH.sub.2 --                                                       N     B.415  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-I      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.416  CH.sub.3 --(CH.sub.2).sub.3 --                            2-I      H       CH.sub.3 --CH.sub.2 --                                                       N     B.417  CH.sub.3 --(CH.sub.2).sub.3 --                            2-I      H       CH.sub.3 --CH.sub.2 --                                                       CH     B.418  CH.sub.3        2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.419  CH.sub.3        2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.420  CH.sub.3 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.421  CH.sub.3 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.422  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.423  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.424  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.425  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.426  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.427  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.428  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.429  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.430  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  N     B.431  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3  CH     B.432  CH.sub.3        2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.433  CH.sub.3        2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.434  CH.sub.3 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.435  CH.sub.3 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.436  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.437  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.438  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.439  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3 --CH.sub.2 --                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.440  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            3-CH.sub.3                                     H       CH.sub.3  N     B.441  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            3-CH.sub.3                                     H       CH.sub.3  CH     B.442  Cl--CH═CH--CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3  N     B.443  Cl--CH═CH--CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3  CH     B.444  CH.sub.3        3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.445  CH.sub.3        3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.446  CH.sub.3 --CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.447  CH.sub.3 --CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.448  CH.sub.3 --CH.sub.2 --CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.449  CH.sub.3 --CH.sub.2 --CH.sub.2                            3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.450  CH.sub.3 --(CH.sub.2).sub.3 --                            3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.451  CH.sub.3 --(CH.sub.2).sub.3 --                            3-CH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.452  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  N     B.453  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  CH     B.454  Cl--CH═CH--CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  N     B.455  Cl--CH═CH--CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3  CH     B.456  CH.sub.3        2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.457  CH.sub.3        2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.458  CH.sub.3 --CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.459  CH.sub.3 --CH.sub.2 --                            2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.460  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.461  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.462  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.463  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.464  CH.sub.3        2-CN     H       CH.sub.3  N     B.465  CH.sub.3        2-CN     H       CH.sub.3  CH     B.466  CH.sub.3 --CH.sub.2                            2-CN     H       CH.sub.3  N     B.467  CH.sub.3 --CH.sub.2                            2-CN     H       CH.sub.3  CH     B.468  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CN     H       CH.sub.3  N     B.469  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CN     H       CH.sub.3  CH     B.470  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CN     H       CH.sub.3  N     B.471  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CN     H       CH.sub.3  CH     B.472  CH.sub.2 ═CH--CH.sub.2 --                            2-CN     H       CH.sub.3  N     B.473  CH.sub.2 ═CH--CH.sub.2 --                            2-CN     H       CH.sub.3  CH     B.474  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CN     H       CH.sub.3  N     B.475  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CN     H       CH.sub.3  CH     B.476  Cl--CH═CH--CH.sub.2 --                            2-CN     H       CH.sub.3  N     B.477  Cl--CH═CH--CH.sub.2 --                            2-CN     H       CH.sub.3  CH     B.478  CH.sub.3        2-CN     H       CH.sub.3 --CH.sub.2 --                                                       N     B.479  CH.sub.3        2-CN     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.480  CH.sub.3 --CH.sub.2                            2-CN     H       CH.sub.3 --CH.sub.2 --                                                       N     B.481  CH.sub.3 --CH.sub.2                            2-CN     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.482  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CN     H       CH.sub.3 --CH.sub.2 --                                                       N     B.483  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CN     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.484  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CN     H       CH.sub.3 --CH.sub.2 --                                                       N     B.485  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CN     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.486  CH.sub.3        2-NO.sub.2                                     H       CH.sub.3  N     B.487  CH.sub.3        2-NO.sub.2                                     H       CH.sub.3  CH     B.488  CH.sub.3 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3  N     B.489  CH.sub.3 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3  CH     B.490  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3  N     B.491  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3  CH     B.492  CH.sub.3 --(CH.sub.2).sub.3 --                            2-NO.sub.2                                     H       CH.sub.3  N     B.493  CH.sub.3 --(CH.sub.2).sub.3 --                            2-NO.sub.2                                     H       CH.sub.3  CH     B.494  CH.sub.2 ═CH--CH.sub.2 --                            2-NO.sub.2                                     H       CH.sub.3  N     B.495  CH.sub.2 ═CH--CH.sub.2 --                            2-NO.sub.2                                     H       CH.sub.3  CH     B.496  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-NO.sub.2                                     H       CH.sub.3  N     B.497  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-NO.sub.2                                     H       CH.sub.3  CH     B.498  Cl--CH═CH--CH.sub.2 --                            2-NO.sub.2                                     H       CH.sub.3  N     B.499  Cl--CH═CH--CH.sub.2 --                            2-NO.sub.2                                     H       CH.sub.3  CH     B.500  CH.sub.3        2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.501  CH.sub.3        2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.502  CH.sub.3 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.503  CH.sub.3 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.504  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.505  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.506  CH.sub.3 --(CH.sub.2).sub.3 --                            2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       N     B.507  CH.sub.3 --(CH.sub.2).sub.3 --                            2-NO.sub.2                                     H       CH.sub.3 --CH.sub.2 --                                                       CH     B.508  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-Cl    CH.sub.3  N     B.509  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-Cl    CH.sub.3  CH     B.510  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-Cl    CH.sub.3  N     B.511  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-Cl    CH.sub.3  CH     B.112  CH.sub.2 ═CH--CH.sub.2 --                            2-Cl     5-Cl    CH.sub.3  N     B.513  CH.sub.2 ═CH--CH.sub.2 --                            2-Cl     5-Cl    CH.sub.3  CH     B.514  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Cl     5-Cl    CH.sub.3  N     B.515  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Cl     5-Cl    CH.sub.3  CH     B.516  Cl--CH═CH--CH.sub.2 --                            2-Cl     5-Cl    CH.sub.3  N     B.517  Cl--CH═CH--CH.sub.2 --                            2-Cl     5-Cl    CH.sub.3  CH     B.518  CH.sub.3        2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.519  CH.sub.3        2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.520  CH.sub.3 --CH.sub.2                            2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.521  CH.sub.3 --CH.sub.2                            2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.522  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.523  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.524  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.525  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.526  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.527  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.528  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.529  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.530  CH.sub.2 ═CH--CH.sub.2 --                            2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.531  CH.sub.2 ═CH--CH.sub.2 --                            2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.532  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.533  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.534  Cl--CH═CH--CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3  N     B.535  Cl--CH═CH--CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3  CH     B.536  CH.sub.3        2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.537  CH.sub.3        2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.538  CH.sub.3 --CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.539  CH.sub.3 --CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.540  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.541  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.542  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.543  CH.sub.3 --(CH.sub.2).sub.3 --                            2-Cl     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.544  CH.sub.3        2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.545  CH.sub.3        2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.546  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.547  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.548  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.549  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.550  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.551  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.552  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.553  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.554  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.555  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.556  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  N     B.557  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     5-Cl    CH.sub.3  CH     B.558  CH.sub.3        2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.559  CH.sub.3        2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.560  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.561  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.562  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.563  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.564  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       N     B.565  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-Cl    CH.sub.3 --CH.sub.2 --                                                       CH     B.566  CH.sub.3        2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.567  CH.sub.3        2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.568  CH.sub.3 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.569  CH.sub.3 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.570  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.571  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.572  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.573  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.574  CH.sub.2 ═CH--CH.sub.2 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.575  CH.sub.2 ═CH--CH.sub.2 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.576  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.577  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.578  Cl--CH═CH--CH.sub.2 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  N     B.579  Cl--CH═CH--CH.sub.2 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3  CH     B.580  CH.sub.3        2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.581  CH.sub.3        2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.582  CH.sub.3 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.583  CH.sub.3 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.584  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.585  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.586  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.587  CH.sub.3 --(CH.sub.2).sub.3 --                            2-OCH.sub.3                                     5-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.588  CH.sub.3        2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.589  CH.sub.3        2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.590  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.591  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.592  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.593  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.594  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.595  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.596  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.597  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.598  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.599  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.600  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  N     B.601  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3  CH     B.602  CH.sub.3        2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.603  CH.sub.3        2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.604  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.605  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.606  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.607  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.608  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       N     B.609  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     6-CH.sub.3                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.610  CH.sub.3        2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.611  CH.sub.3        2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.612  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.613  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.614  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.615  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.616  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.617  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.618  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.619  CH.sub.2 ═CH--CH.sub.2 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.620  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.621  CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.622  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  N     B.623  Cl--CH═CH--CH.sub.2 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3  CH     B.624  CH.sub.3        2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       N     B.625  CH.sub.3        2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.626  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       N     B.627  CH.sub.3 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.628  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       N     B.629  CH.sub.3 --CH.sub.2 --CH.sub.2                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       CH     B.630  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       N     B.631  CH.sub.3 --(CH.sub.2).sub.3 --                            2-CH.sub.3                                     5-CH(CH.sub.3).sub.2                                             CH.sub.3 --CH.sub.2 --                                                       CH     __________________________________________________________________________

                  TABLE C     ______________________________________     Comp. no.             R.sup.1   R.sup.2 R.sup.3                                   R.sup.4                                        R.sup.5                                             R.sup.6                                                  X     ______________________________________     C.001   CH.sub.3 --                       2-CH.sub.3                               H   CH.sub.3                                        CH.sub.3                                             CH.sub.3                                                  N     C.002   CH.sub.3 --                       3-CH.sub.3                               H   CH.sub.3                                        CH.sub.3                                             CH.sub.3                                                  CH     C.003   CH.sub.3 --CH.sub.2                       2-CH.sub.3                               H   CH.sub.3                                        CH.sub.3                                             CH.sub.3                                                  N     C.004   CH.sub.3 --CH.sub.2                       2-CH.sub.3                               H   CH.sub.3                                        CH.sub.3                                             CH.sub.3                                                  CH     C.005   CH.sub.3  2-CH.sub.3                               H   CH.sub.3                                        H    H    N     C.006   CH.sub.3  2-CH.sub.3                               H   CH.sub.3                                        H    H    CH     C.007   CH.sub.3  2-CH.sub.3                               H   CH.sub.3                                        H    C.sub.2 H.sub.5                                                  N     C.008   CH.sub.3  2-CH.sub.3                               H   CH.sub.3                                        H    C.sub.2 H.sub.5                                                  CH     C.009   CH.sub.3  2-CH.sub.3                               H   CH.sub.3                                        CH.sub.3                                             C.sub.2 H.sub.5                                                  CH     ______________________________________

                                      TABLE D     __________________________________________________________________________     Comp. no.            R.sup.1             R.sup.2                                      R.sup.3                                          X     __________________________________________________________________________     D.001  CH.sub.3 --         H     H   CH     D.002  CH.sub.3 --         H     H   N     D.003  CH.sub.3 --         2-Cl  H   CH     D.004  CH.sub.3 --         2-Cl  H   N     D.005  CH.sub.3 --         2-CH.sub.3                                      H   CH     D.006  CH.sub.3 --         2-CH.sub.3                                      H   N     D.007  CH.sub.3 --         2-OCH.sub.3                                      H   CH     D.008  CH.sub.3 --         2-OCH.sub.3                                      H   N     D.009  CH.sub.3 --         3-Cl  H   CH     D.010  CH.sub.3 --         3-Cl  H   N     D.011  CH.sub.3 --         3-CH.sub.3                                      H   CH     D.012  CH.sub.3 --         3-CH.sub.3                                      H   N     D.013  CH.sub.3 --         3-OCH.sub.3                                      H   CH     D.014  CH.sub.3 --         3-OCH.sub.3                                      H   N     D.015  CH.sub.3            2-Cl  6-Cl                                          CH     D.016  CH.sub.3            2-Cl  6-Cl                                          N     D.017  CH.sub.3 --CH.sub.2 --                                H     H   CH     D.018  CH.sub.2 --CH.sub.2 --                                H     H   N     D.019  CH.sub.3 --CH.sub.2 --                                2-Cl  H   CH     D.020  CH.sub.3 --CH.sub.2 --                                2-Cl  H   N     D.021  CH.sub.3 --CH.sub.2 --                                2-CH.sub.3                                      H   CH     D.022  CH.sub.3 --CH.sub.2 --                                2-CH.sub.3                                      H   N     D.023  CH.sub.3 --CH.sub.2 --                                2-OCH.sub.3                                      H   CH     D.024  CH.sub.3 --CH.sub.2 --                                2-OCH.sub.3                                      H   N     D.025  CH.sub.3 --CH.sub.2 --                                3-Cl  H   CH     D.026  CH.sub.3 --CH.sub.2 --                                3-Cl  H   N     D.027  CH.sub.3 --CH.sub.2 --                                3-CH.sub.3                                      H   CH     D.028  CH.sub.3 --CH.sub.2 --                                3-CH.sub.3                                      H   N     D.029  CH.sub.3 --CH.sub.2 --                                3-OCH.sub.3                                      H   CH     D.030  CH.sub.3 --CH.sub.2 --                                3-OCH.sub.3                                      H   N     D.031  CH.sub.3 --CH.sub.2 --                                2-Cl  H   CH     D.032  CH.sub.3 --CH.sub.2 --                                2-Cl  6-Cl                                          N     D.033  CH.sub.3 --CH.sub.2 --CH.sub.2 --                                H     6-Cl                                          CH     D.034  CH.sub.3 --CH.sub.2 --CH.sub.2 --                                H     H   N     D.035  CH.sub.2 ═CH--CH.sub.2 --                                H     H   CH     D.036  CH.sub.2 ═CH--CH.sub.2 --                                H     H   N     D.037  CH.sub.3 --CH(CH.sub.3)--                                H     H   CH     D.038  CH.sub.3 --CH(CH.sub.3)--                                H     H   N     D.039  HC.tbd.C--CH.sub.2 --                                H     H   CH     D.040  HC.tbd.C--CH.sub.2 --                                H     H   N     D.041  cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                H     H   CH     D.042  cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                H     H   N     D.043  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                H     H   CH     D.044  CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                H     H   N     D.045  CH.sub.3 --CH═CH--CH.sub.2 --                                H     H   CH     D.046  CH.sub.3 --CH═CH--CH.sub.2 --                                H     H   N     D.047  CH.sub.3 --(CH.sub.2).sub.5 --                                H     H   CH     D.048  CH.sub.3 --(CH.sub.2).sub.5 --                                H     H   N     D.049  cyclo-C.sub.6 H.sub.11 --                                H     H   CH     D.050  cyclo-C.sub.6 H.sub.11 --                                H     H   N     D.051  C.sub.6 H.sub.5 --CH.sub.2 --                                H     H   CH     D.052  C.sub.6 H.sub.5 --CH.sub.2 --                                H     H   N     D.053  4-Cl-C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   CH     D.054  4-Cl-C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   N     D.055  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   CH     D.056  3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   N     D.057  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   CH     D.058  4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   N     D.059  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                H     H   CH     D.060  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                H     H   N     D.061  C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                H     H   CH     D.062  C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                H     H   N     D.063  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                H     H   CH     D.064  C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                H     H   N     D.065  4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                                H     H   CH     D.066  4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                                H     H   N     D.067  t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                H     H   CH     D.068  t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                H     H   N     D.069  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                H     H   CH     D.070  t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                H     H   N     D.071  Cl--CH═CH--CH.sub.2 --                                H     H   CH     D.072  Cl--CH═CH--CH.sub.2 --                                H     H   N     D.073  C.sub.2 H.sub.5     6-OC.sub.2 H.sub.5                                      H   CH     D.074  C.sub.2 H.sub.5     6-OC.sub.2 H.sub.5                                      H   N     D.075  CH.sub.3 --C(CH.sub.3).sub.2 --                                H     H   CH     D.076  CH.sub.3 --C(CH.sub.3).sub.2 --                                H     H   N     D.077  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                H     H   CH     D.078  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                H     H   N     D.079  CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                                H     H   CH     D.080  CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                                H     H   N     D.081  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                                H     H   CH     D.082  CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                                H     H   N     D.083  CH.sub.3 --(CH.sub.2).sub.4 --                                H     H   CH     D.084  CH.sub.3 --(CH.sub.2).sub.4 --                                H     H   N     D.085  2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   CH     D.086  2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   N     D.087  3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   CH     D.088  3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   N     D.089  2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   CH     D.090  2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                H     H   N     D.091  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                H     H   CH     D.092  3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                H     H   N     D.093  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                H     H   CH     D.094  2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                H     H   N     D.095  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                H     H   CH     D.096  C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                H     H   N     D.097  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                                H     H   CH     D.098  C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                                H     H   N     D.099  4-Cl--C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                H     H   CH     D.100  4-Cl--C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                H     H   N     D.101  4-CF.sub.3 --C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                H-    H   CH     D.102  4-CF.sub.3 --C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                H-    H   N     __________________________________________________________________________

                  TABLE E     ______________________________________     Comp. no.              R.sup.1          R.sup.2  R.sup.3     ______________________________________     E.001    CH.sub.3         2-CH.sub.3                                        5-CH.sub.3     E.002    CH.sub.3 CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.003    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.004    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.005    HC.tbd.C--CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.006    CH.sub.2 ═CH--CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.007    CH.sub.3 --CH═CH--CH.sub.2                               2-CH.sub.3                                        5-CH.sub.3     E.008    C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.009    CH.sub.3         2-CH.sub.3                                        2-Cl     E.010    CH.sub.3 CH.sub.2 --                               2-CH.sub.3                                        2-Cl     E.011    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        2-Cl     E.012    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        2-Cl     E.013    CH.sub.2 ═CH--CH.sub.2 --                               2-CH.sub.3                                        2-Cl     E.014    C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                               2-CH.sub.3                                        2-Cl     E.015    CH.sub.3         2-CH.sub.3                                        5-isopropyl     E.016    CH.sub.3 CH.sub.2 --                               2-CH.sub.3                                        5-isopropyl     E.017    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        5-isopropyl     E.018    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        5-isopropyl     E.019    CH.sub.2 ═CH--CH.sub.2 --                               2-CH.sub.3                                        5-isopropyl     E.020    C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                               2-CH.sub.3                                        5-isopropyl     E.021    CH.sub.3         2-Cl     5-Cl     E.022    CH.sub.3 CH.sub.2 --                               2-Cl     5-Cl     E.023    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-Cl     5-Cl     E.024    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-Cl     5-Cl     E.025    HC.tbd.C--CH.sub.2 --                               2-Cl     5-Cl     E.026    CH.sub.2 ═CH--CH.sub.2 --                               2-Cl     5-Cl     E.027    C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                               2-Cl     5-Cl     E.028    CH.sub.3         2-F      H     E.029    CH.sub.3 CH.sub.2 --                               2-F      H     E.030    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-F      H     E.031    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-F      H     E.032    HC.tbd.C--CH.sub.2 --                               2-F      H     E.033    CH.sub.2 ═CH--CH.sub.2 --                               2-F      H     E.034    CH.sub.3         2-Cl     5-CH.sub.3     E.035    CH.sub.3 CH.sub.2 --                               2-Cl     5-CH.sub.3     E.036    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-Cl     5-CH.sub.3     E.037    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-Cl     5-CH.sub.3     E.038    HC.tbd.C--CH.sub.2 --2-Cl                               5-CH.sub.3     E.039    CH.sub.2 ═CH--CH.sub.2 --                               2-Cl     5-CH.sub.3     E.040    CH.sub.3         2-CN     H     E.041    CH.sub.3 CH.sub.2 --                               2-CN     H     E.042    CH.sub.3 (CH.sub.2).sub.4 --                               2-CH.sub.3                                        5-CH.sub.3     E.043    CH.sub.3 (CH.sub.2).sub.5 --                               2-CH.sub.3                                        5-CH.sub.3     E.044    C.sub.6 H.sub.5 --CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.045    t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.046    Cl--CH═CH--CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.047    CH.sub.3 O--CH.sub.2 --CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     E.048    CH.sub.3 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        H     E.049    CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                               2-CH.sub.3                                        H     E.050    CH.sub.3 (CH.sub.2).sub.4 --                               2-CH.sub.3                                        H     E.051    CH.sub.3 (CH.sub.2).sub.5 --                               2-CH.sub.3                                        H     E.052    CH.sub.3 (CH.sub.2).sub.6 --                               2-CH.sub.3                                        H     E.053    HC.tbd.C--CH.sub.2 --                               2-CH.sub.3                                        H     E.054    CH.sub.2 ═CH--CH.sub.2 --                               2-CH.sub.3                                        H     E.055    CH.sub.3 --CH═CH--CH.sub.2 --                               2-CH.sub.3                                        H     E.056    C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                               2-CH.sub.3                                        H     E.057    CH.sub.3 O--CH.sub.2 --CH.sub.2 --                               2-CH.sub.3                                        H     E.058    C.sub.6 H.sub.5 --CH.sub.2 --                               2-CH.sub.3                                        H     E.059    Cl--CH═CH--CH.sub.2 --                               2-CH.sub.3                                        H     E.060    t-C.sub.4 H.sub.9 O--CH--CH.sub.2 --                               2-CH.sub.3                                        H     E.061    cyclo-C.sub.6 H.sub.11 --                               2-CH.sub.3                                        H     E.062    (CH.sub.3).sub.2 --CH--                               2-CH.sub.3                                        H     E.063    t-butyl-         2-CH.sub.3                                        H     E.064    (CH.sub.3).sub.2 --CH--CH.sub.2 --                               2-CH.sub.3                                        H     E.065    (CH.sub.3).sub.2 --CH--                               2-CH.sub.3                                        5-CH.sub.3     E.066    t-butyl-         2-CH.sub.3                                        5-CH.sub.3     E.067    (CH.sub.3).sub.2 --CH--CH.sub.2 --                               2-CH.sub.3                                        5-CH.sub.3     ______________________________________

In general terms, the novel compounds I are extremely effective on a broad spectrum of phytopathogenic fungi, in particular those from the class consisting of the Ascomycetes and Basidiomycetes. Some of them have a remarkably high systemic mobility and action after application to the soil and particularly to foliage.

The fungicidal compounds are of particular interest for controlling a large number of fungi in various crops or their seeds, especially wheat, rye, barley, oats, rice, Indian corn, lawns, cotton, soybeans, coffee, sugar cane, fruit and ornamentals in horticulture and viticulture, and in vegetables such as cucumbers, beans and cucurbits.

The novel compounds are particularly useful for controlling the following plant diseases:

Erysiphe graminis in cereals,

Erysiphe cichoracearum and Sphaerotheca fuliginea in cucurbits,

Podosphaera leucotricha in apples,

Uncinula necator in vines,

Puccinia species in cereals,

Rhizoctonia solani in cotton,

Ustilago species in cereals and sugar cane,

Venturia inaequalis (scab) in apples,

Helminthosporium species in cereals,

Septoria nodorum in wheat,

Botrytis cinerea (gray mold) in strawberries and grapes,

Cercospora arachidicola in groundnuts,

Pseudocercosporella herpotrichoides in wheat and barley,

Pyricularia oryzae in rice,

Phytophthora infestans in potatoes and tomatoes,

Fusarium and Verticillium species in various plants,

Plasmopara viticola in grapes,

Alternaria species in fruit and vegetables.

The compounds I are applied by spraying or dusting the plants with the active ingredients, or treating the seeds of the plants with the active ingredients. They may be applied before or after infection of the plants or seeds by the fungi.

The novel substances can be converted into conventional formulations such as solutions, emulsions, suspensions, dusts, powders, pastes and granules. The application forms depend entirely on the purposes for which they are intended; they should at all events ensure a fine and uniform distribution of the active ingredient. The formulations are produced in known manner, for example by extending the active ingredient with solvents and/or carriers, with or without the use of emulsifiers and dispersants; if water is used as solvent, it is also possible to employ other organic solvents as auxiliary solvents. Suitable auxiliaries for this purpose are solvents such as aromatics (e.g., xylene), chlorinated aromatics (e.g., chlorobenzenes), paraffins (e.g., crude oil fractions), alcohols (e.g., methanol, butanol), ketones (e.g., cyclohexanone), amines (e.g., ethanolamine, dimethylformamide), and water; carriers such as ground natural minerals (e.g., kaolins, aluminas, talc and chalk) and ground synthetic minerals (e.g., highly disperse silica and silicates); emulsifiers such as nonionic and anionic emulsifiers (e.g., polyoxyethylene fatty alcohol ethers, alkyl sulfonates and aryl sulfonates); and dispersants such as lignin-sulfite waste liquors and methylcellulose.

The fungicides generally contain from 0.1 to 95, and preferably from 0.5 to 90, wt% of active ingredient. The application rates are from 0.02 to 3 kg or more of active ingredient per, hectare, depending on the type of effect desired.

When the active ingredients are used for treating seed, application rates of from 0.001 to 50, and preferably from 0.01 to 10, g per kg of seed are generally required.

When the agents according to the invention are used as fungicides, they may be employed together with other active ingredients, e.g., herbicides, insecticides, growth regulators, other fungicides and fertilizers.

When admixed with other fungicides, the spectrum of fungicidal action is in many instances increased.

The compounds of the formula IA are suitable for effectively combating pests such as insects, arachnids and nematodes. They may be used as pesticides in crop protection and in the hygiene, stores protection and veterinary sector.

Examples of injurious insects belonging to the Lepidoptera order are Agrotis ypsilon, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholita funebrana, Grapholita molesta, Heliothis armigera, Heliothis virescens, Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keifferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossygpiella, Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Phyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni and Zeiraphera canadensis.

Examples from the Coleoptera order are Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Ceuthorrhynchus assimilis, Ceuthorrynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Diabrotica longicornis, Diabrotica 12-punctata, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllotreta chrysocephala, Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitona lineatus and Sitophilus granaria.

Examples from the Diptera order are Aedes aegypti, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Contarinia sorghicola, Cordylobia anthopophaga, Culex pipiens, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Fannia canicularis, Gasterophilus intestinalis, Glossina morsitans, Haematobia irritans, Haplodiplosis eguestris, Hylemyia platura, Hypoderma lineata, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mayetiola destructor, Musca domestica, Muscina stabulans, Oestrus ovis, Oscinella frit, Pegomya hyoscyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Rhagoletis cerasi, Rhagoletis pomonella, Tabanus bovinus, Tipula oleracea and Tipula paludosa.

Examples from the Thysanoptera order are Frankliniella fusca, Frankliniella occidentalis, Franklinleila tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi and Thrips tabaci.

Examples from the Hymenoptera order are Athalia rosae, Atta cephalotes, Atta sexdens, Atta texana, Hoplocampa minuta, campa testudinea, Monomorium pharaonis, Solenopsis geminata and Solenopsis invicta.

Examples from the Heteroptera order are Acrosternum hilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, Lygus prapensis, Nezara viridula, Piesma quadrata, Solubea insularis and Thyanta perditor.

Examples from the Homoptera order are Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis pomi, Aphis sambuci, Bemisia tabaci, Brachycaudus cardui, Brevicoryne brassicae, Cerosipha gossypii, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Empoasca fabae, Macrosiphum avenae, Macrosiphum euphorbiae, Macrosiphon rosae, Megoura viciae, Metopolophium dirhodum, Myzodes persicae, Myzus cerasi, Nephotettix cincticeps, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Sappahis mall, Schizaphis graminum, Schizoneura lanuginosa, Trialeurodes vaporariorum and Viteus vitifolii.

Examples from the Isoptera order are Calotermes flavicollis, Leucotermes flavipes, Retuculitermes lucifugus and Termes natalentsis.

Examples from the Orthoptera order are Acheta domestica, Blatta orientalis, Blattella germanica, Forficula auricularia, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus biviptatus, Melanoplus femur-rubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Periplaneta americana, Schistocerca americana, Schistocerca peregrina, Stauronotus maroccanus and Tachycines asynamorus.

Examples from the Acarina order are Amblyomma americanum, Amblyomma variegatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Brevipalpus phoenicis, Bryobia praetiosa, Dermacentor silvarum, Eotetranychus carpini, Eriophyes sheldoni, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Metatetranychus (Panonychus) ulmi, Ornithodorus moubata, Otobins megnini, Paratetranychus pilosus, Dermanyssus gallinae, Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes ovis, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae.

Examples from the nematodes class are root-knot nematodes, e.g., Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica, Zysten bildende Nematoden, z.B. Globodera rostochiensis, Heterodera avenae, Heterodera glycinae, Heterodera schachtii, Heterodera trifolii, Stock- und Blattalchen, z.B. Belonolaimus longicaudatus, Ditylenchus destructor, Ditylenchus dipsaci, Heliocotylenchus multicinctus, Longidorus elongatus, Radopholus similis, Rotylenchus robustus, Trichodorus primitivus, Tylenchorhynchus claytoni, Tylenchorhynchus dubius, Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus and Pratylenchus goodeyi.

The active ingredients may be applied for instance as such, or in the form of formulations or application forms prepared therefrom, e.g., directly sprayable solutions, powders, suspensions, dispersions, emulsions, oil dispersions, pastes, dusts, broadcasting agents, or granules by spraying, atomizing, dusting, broadcasting or watering. The forms of application depend entirely on the purpose for which the agents are being used, but they must ensure as fine a distribution of the active ingredients according to the invention as possible.

The active ingredient concentrations in the finished formulations may vary within wide limits, but are generally from 0.0001 to 10, and preferably from 0.01 to 1%.

The active ingredients may also be successfully used in the ultra-low-volume (ULV) method, where it is possible to apply formulations containing more than 95 wt% of active ingredient, or the active ingredient without any additives at all.

When the active ingredients are used for combating pests in the open, the application rates are from 0.1 to 2.0, and preferably from 0.2 to 1.0, kg/ha.

For the preparation of solutions, emulsions, pastes and oil dispersions to be sprayed direct, mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, further coal-tar oils, and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons such as toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes and their derivatives, methanol, ethanol, propanol, butanol, cyclohexanol, cyclohexanone, chlorobenzene, isophorone, etc., and strongly polar solvents such as N,N-dimethylformamide, dimethyl sulfoxide, N-methylpyrrolidone, water, etc. are suitable.

Aqueous formulations may be prepared from emulsion concentrates, pastes, oil dispersions, wettable powders or water-dispersible granules by adding water. To prepare emulsions, pastes and oil dispersions the ingredients as such or dissolved in an oil or solvent may be homogenized in water by means of wetting or dispersing agents, adherents or emulsifiers. Concentrates which are suitable for dilution with water may be prepared from active ingredient, wetting agent, adherent, emulsifying or dispersing agent and possibly solvent or oil.

Examples of surfactants are: alkali metal, alkaline earth metal and ammonium salts of aromatic sulfonic acids, e.g., ligninsulfonic acid, phenolsulfonic acid, naphthalenesulfonic acid and dibutylnaphthalenesulfonic acid, and of fatty acids, alkyl and alkylaryl sulfonates, and alkyl, lauryl ether and fatty alcohol sulfates, and salts of sulfated hexadecanols, heptadecanols, and octadecanols, salts of fatty alcohol glycol ethers, condensation products of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensation products of naphthalene or naphthalenesulfonic acids with phenol and formaldehyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol, ethoxylated octylphenol and ethoxylated nonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, alkylaryl polyether alcohols, isotridecyl alcohol, fatty alcohol ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignin-sulfite waste liquors and methyl cellulose.

Powders, dusts and broadcasting agents may be prepared by mixing or grinding the active ingredients with a solid carrier.

The formulations generally contain from 0.01 to 95, and preferably from 0.1 to 90, wt % of active ingredient. The active ingredients are used in a purity of from 90 to 100, and preferably from 95 to 100% (according to the NMR spectrum).

Granules, e.g., coated, impregnated or homogeneous granules, may be prepared by bonding the active ingredients to solid carriers. Examples of solid carriers are mineral earths such as silicic acids, silica gels, silicates, talc, kaolin, attapulgus clay, limestone, lime, chalk, bole. loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground plastics, fertilizers such as ammonium sulfate, ammonium phosphate. ammonium nitrate, and ureas, and vegetable products such as grain meals, bark meal, wood meal, and nutshell meal, cellulosic powders, etc.

Examples of formulations are as follows:

Granules, e.g., coated, impregnated or homogeneous granules; they may be prepared by bonding the active ingredients to solid carriers. Examples of solid carriers are mineral earths such as silicic acids, silica gels, silicates, talc, kaolin, attapulgus clay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground plastics, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, and ureas, and vegetable products such as grain meals, bark meal, wood meal, and nutshell meal, cellulosic powders, etc.

The active ingredients may also be applied together with other crop protection agents such as herbicides, fungicides other pesticides and bactericides. These agents may be added to the agents according to the invention in a weight ratio of from 1:10 to 10:1, if desired immediately prior to use (tankmix).

In these application forms, the agents according to the invention may also be present together with other active ingredients, for example herbicides, insecticides, growth regulators, and fungicides, and may furthermore be mixed and applied together with fertilizers. Admixture with other fungicides frequently results in a greater fungicidal action spectrum.

Examples demonstrating the action on injurious fungi

For comparison purposes the following compounds were used:

2-(2'-methylphenoxymethyl)-phenylglyoxylic acid methyl ester-O-methyloxime (A) having the formula ##STR11## and 2-(2'-methyl-4'-(methoximinoeth-1"-yl) -phenoxymethyl)phenylglyoxylic acid methyl ester-O-methyloxime (B) having the formula ##STR12## A.1 Action on Plasmopara viticola

Leaves of potted vines of the Muller-Thurgau variety were sprayed with aqueous suspensions containing (dry basis) 80% of active ingredient and 20% of emulsifier. To assess the duration of action, the plants were set up, after the sprayed-on layer had dried, for 8 days in the greenhouse. Then the leaves were infected with a zoospore suspension of Plasmopara viticola. The plants were first placed for 48 hours in a water vapor-saturated chamber at 24° C. and then in a greenhouse for 5 days at from 20° to 30° C. To accelerate and intensify the sporangiophore discharge, the plants were then again placed in the moist chamber for 16 hours. The extent of fungus attack was then assessed on the undersides of the leaves.

    ______________________________________                Percentage leaf attack after applying aqueous     Active in- formulations containing . . . ppm of active     gredient   ingredient     no.        60 ppm                15 ppm     ______________________________________     I.007      0                     0     I.011      0                     0     Untreated              65     ______________________________________

A.2 Action on wheat brown rust

Leaves of pot-grown wheat seedlings of the "Kanzler" variety were dusted with spores of brown rust (Puccinia recondita). The pots were then placed for 24 hours at 20° to 22° C. in a high-humidity (90-95%) chamber. During this period the spores germinated and the germ tubes penetrated the leaf tissue. The infected plants were then sprayed to runoff with aqueous liquors containing (dry basis) 80% of active ingredient and 20% of emulsifier. After the sprayed-on layer had dried, the plants were set up in the greenhouse at 20° to 22° C. and a relative humidity of 65 to 70%. The extent of rust fungus spread on the leaves was assessed after 8 days.

    ______________________________________                 Percentage leaf attack after application of     Active in-  aqueous formulations containing . . . ppm of     gredient    active ingredient     no.         60 ppm                15 ppm     ______________________________________     I.007       0                     0     I.011       0                     0     Untreated               70     ______________________________________

A.3 Action on bean rust

The undersides of leaves of bush beans of the "Fori" variety were uniformly sprayed with an aqueous spore suspension of bean rust (Uromyces appendiculatus). The plants were then kept for 24 hours in a high-humidity climatic cabinet at 19° C. and then set up in the greenhouse at 22° to 25° C. After 2 to 3 days the lower (basal) half of the upper side of the leaves was sprayed with the active ingredients. Fungus spread was assessed 10 to 12 days after spraying. As a result of the temporal and spatial separation of leaf treatment with the spores and leaf treatment with the active ingredients, there is no direct contact between fungus and active ingredient; consequently, the fungicidal action must have been preceded by active ingredient uptake and migration (systemic transport) in the leaf. By examining the various leaf zones it is possible to ascertain whether translaminar or apical movement of the candidate active ingredients has taken place in the leaf.

The results of the experiment show that, after treatment with a spray liquor containing 50 ppm of active ingredient, active ingredients nos. I.003, I.007 and I.014 had a fungicidal action on the leaf undersides and in part on the untreated portion of the bean leaves, whereas the prior art comparative compounds A and B had no fungicidal action.

Use examples demonstrating the action on pests

The action of compounds of the general formula IA on pests from the class of insects, mites and nematodes may be demonstrated by the following experiments:

The active ingredients were formulated

a) as a 0.1% strength solution in acetone, or

b) as a 10% strength emulsion in a mixture of 70 wt % of cyclohexanol, 20 wt % of Nekanil®LN (Lutensol®AP6, a spreader-sticker with an emulsifying and dispersing action based on ethoxylated alkylphenols) and 10 wt % of EmulphorI EL (Emulan® EL, an emulsifier based on ethoxylated fatty alcohols)

and diluted to the desired concentration with acetone in the case of a) and with water in the case of b).

Upon conclusion of the experiments the lowest concentration was determined at which the compounds, compared with the untreated controls, achieved 80% inhibition or kill (action threshold or minimum concentration).

B.1 Aphis fabae, contact action

Bush beans (Vicia faba) under heavy louse attack were treated with aqueous formuations of the active ingredients.

The kill rate was determined after 24 hours.

In this test, compounds nos. I.007, I.011, I.015, I.003, I.001, I.017, I.058, I.086, I.096 and I.029 exhibited action thresholds of from 200 to 1000 ppm.

B.2 Nephotettix cincticeps, contact action

Circular filter papers were treated with aqueous formulations of the active ingredients; 5 adult leafhoppers were then placed on the filter papers.

The kill rate was determined after 24 hours.

In this test, compounds nos. I.007, I.011, I.014, I.015, I.003, I.002, I.004, I.017, I.117, I.307, I.192, I.193, I.195 and I.201 exhibited action thresholds of from 0.4 to 0.1 mg.

B.3 Prodenia litura, breeding experiment

Five caterpillars in the development stage L3 (10-12 mm) were placed on a standard nutrient medium (3.1 liters of water, 80 g of agar, 137 g of brewer's yeast, 515 g of corn-flour, 130 g of wheat germ, and conventional additives and vitamins (20 g of Wessons salt, 5 g of Nipagin, 5 g of sorbic acid, 10 g of cellulose powder, 18 g of ascorbic acid, 1 g of Lutavit® blend (vitamin) and 5 ml of alcoholic biotin solution)) which had previously been wetted with aqueous formulations of the active ingredients.

Observation extended up to emergence of the moths in a control experiment without active ingredient.

In this test, compounds nos. I.003, I.014, I.015, I.017, I.057, I.064, I.068, I.076, I.100, I.108, I.109, I.112, I.119 and I.079 exhibited action thresholds of from 200 to 0.1 ppm.

B.4 Agrotis ypsilon, contact action

Corn leaves were dipped for 3 seconds in aqueous formulations of the active ingredients and placed, after excess liquid had been allowed to drip off, on circular filter papers in a Petri dish 12 cm in diameter. 5 caterpillars in the third and fourth larval stages (about 15 mm long) were placed in each dish.

The action in % feeding inhibition and % kill was assessed after 24 and 48 hours.

In this test, compounds nos. I.060, I.070, I.086, I.090, I.096, I.117, I.121, I.129, I.140, I.177, I.307, I.189, I.190, I.191, I.192, I.193, I.195, I.201 and I.213 exhibited a threshold action of from 10 to 1000 ppm.

B.5 Sitophilus granaria, contact action

The bottoms of experimental vessels were treated with acetonic solutions of the active ingredients. After the acetone had evaporated, about 50 weevils were introduced into each dish.

After 4 hours, the weevils were transferred to cardboard dishes, which were then placed in the experimental vessels.

The action was determined after 24 hours in percentage kill. Weevils unable to leave the cardboard dishes were considered to be dead or heavily damaged.

In this test, compound no. I.115 exhibited an action threshold of 1 mg.

B.6 Musca domestica, contact experiment

The bottoms of experimental vessels were wetted with acetonic solutions of the active ingredients and, after the solvent had evaporated, 10 flies were placed in each vessel.

The kill rate was determined after 4 hours.

In this test, confounds nos. I.064, I.071, I.077, I.078, I.080, I.083, I.085, I.098, I.100, I.103, I.106, I.111, I.115, I.117, I.126, I.127, I.130, I.133, I.309 and I.184 exhibited an action threshold of from 0.01 to 2 mg.

B.7 Musca domestica, breeding experiment

25 ml of a dry feed mix (1 kg of bran, 250 g of yeast powder, 35 g of fish meal) was mixed with the active ingredients and 25 ml of a milk-sugar solution (1 liter of milk and 42 g of sugar) and 20 larvae of the first development stage were then placed on it.

The kill rate was determined after the larvae in a control experiment had hatched.

In this test, compound no. I.064 exhibited an action threshold of 40 ppm.

B.8 Prodenia litura, contact experiment

Circular filter papers 9 cm in diameter were treated with 1 cm³ of aqueous formulations of the active ingredients and then placed in a plastic Petri dish 94 mm in diameter. 5 Prodenia caterpillars L3 were then introduced into each dish and the dishes were closed. Assessment took place after 24 hours.

In this test, compounds nos. I.098, I.100, I.102, I.106, I.111, I.115 and I.184 exhibited an action threshold of from 0.1 to 1 mg.

B.9 Prodenia litura, breeding experiment

Five caterpillars in the development stage L3 (10-12 mm) were placed on a standard nutrient medium (3.1 liters of water, 80 g of agar, 137 g of brewer's yeast, 515 g of corn-flour, 130 g of wheat germ, and conventional additives and vitamins (20 g of Wessons salt, 5 g of Nipagin, 5 g of sorbic acid, 10 g of cellulose powder, 18 g of ascorbic acid, 1 g of Lutavit® blend (vitamin) and 5 ml of alcoholic biotin solution)) which had previously been wetted with aqueous formulations of the active ingredients.

Observation extended up to emergence of the moths in a control experiment without active ingredient.

In this test, compounds nos. I.128, I.272, I.292, I.293, I.307 and I.310 exhibited an action threshold of from 1 to 1000 ppm.

B.10 Plutella maculipennis, contact action

Leaves of young cabbage plants were wetted with aqueous solutions of the active ingredients and then placed on moistened filter papers. 10 caterpillars in the fourth development stage were then placed on the leaves prepared in this way.

The kill rate was determined after 48 hours.

In this test, compounds nos. I.064, I.065, I.068, I.079, I.081, I.084, I.086, I.088, I.090, I.117 and I1.130 exhibited an action threshold of from 200 to 1000 ppm.

B.11Aedes aegypti, breeding experiment

Plastic beakers 8 cm in diameter and holding 250 ml were filled with 200 ml of tapwater of 23° C.; 30-40 Aedes larvae in the third to fourth larval stage were then introduced into each beaker. The candidate compounds are then added as aqueous emulsions or suspensions to the vessels and the kill rate is determined after 24 hours. Breeding is then continued until the mosquitoes emerge. The room temperature is 25° C.

In this test, compound no. I.128 exhibited an action threshold of 0.1 ppm. 

We claim:
 1. A method for controlling pests selected from the group consisting of insects, arachnids and nematodes comprising treating the pests or their infected habitat with an effective amount of a compound of the formula IA: ##STR13## where R¹ is C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₄ -alkynyl, C₁ -C₆ -haloalkyl, C₃ -C₆ -haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl, C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl, cyano-C₁ -C₆ -alkyl, C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl, aryl-C₃ -C₆ -alkyl, pyridyl-C₁ -C₆ -alkyl, thienyl-C₁ -C₆ -alkyl, aryl-C₁ -C₆ -alkenyl or aryloxy-C₁ -C₆ -alkyl, where the aromatic or heteroaromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₃ -C₆ -cycloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, aryl or aryloxy,R² and R³ are identical or different and are each hydrogen, C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro, R⁴ is hydrogen, C₁ -C₆ -alkyl or aryl, where the aromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro, X is CH or N, and Z is a group NR⁵ R⁶, where R⁵ and R⁶ are identical or different and are each hydrogen or C₁ -C₄ -alkyl.
 2. A method for controlling insects, arachnids, or nematodes as set forth in claim 1, wherein in the compound of the formula IA, R¹, R² (in the 2-position), R⁴ and R⁶ are each methyl, R³ and R⁵ are each hydrogen, X is N and the oximinoethyl radical is in the 4-position.
 3. A method for controlling insects, arachnids or nematodes as set forth in claim 1, wherein in the compound of the formula IA, R¹, R² (in the 2-position), R⁴ and R⁶ are each methyl, R³ and R⁵ are each hydrogen, X is CH and the oximinoethyl radical is in the 4-position.
 4. A method for controlling insects, arachnids or nematodes as set forth in claim 1, wherein in the compound of the formula IA, R¹ is methyl, R² in the 2-position is methyl, R⁴ is cyclopropyl, R⁶ is methyl, R³ and R⁵ are each hydrogen, X is N and the oximino radical is in the 4-position.
 5. A method for controlling insects, arachnids or nematodes as set forth in claim 1, wherein in the compound of the formula IA, R¹ is methyl, R² in the 2-position is methyl, R⁴ is trifluoromethyl, R⁶ is methyl, R³ and R⁵ are each hydrogen, X is N and the oximino radical is in the 4-position. 